Activin RIIA Antibody (60401) [Alexa Fluor® 594]

• Reactivity: Hu
• Applications: WB
• Clone: 60401
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 594

Activin RIIA Antibody (60401) [Alexa Fluor® 594] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Activin RIIB
  Ser19-Thr134
  Accession # Q13705
• Specificity: Detects human Activin RII in direct ELISA and Western blots.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Activin RIIA Antibody (60401) [Alexa Fluor® 594]

• activin A receptor, type II
• activin A receptor, type IIA
• Activin receptor type IIA
• activin receptor type-2A
• Activin RIIA
• ActivinRIIA
• ACTRII
• ACTRIIA
• ACVR2A
• ACVR2ACTR-IIA
• AVR2A
• EC 2.7.11
• EC 2.7.11.30

Background

Members of the TGF- beta superfamily exert their biological effects by binding to heteromeric complexes of a type I and a type II serine-threonine kinase receptor, both of which are essential for signal transduction. Activin receptor type IIB is a type II receptor that mediates multiple signals for transforming growth factor-beta (TGF-beta) family members, including Activin, Nodal, Bmp7, GDF1, GDF3, Myostatin (GDF8), and GDF11. Through alternative mRNA splicing, multiple ActR-IIB isoforms can also be generated.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.