Activin A Antibody (725818) [Alexa Fluor® 405]

• Reactivity: Mu
• Applications: WB
• Clone: 725818
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 405

Activin A Antibody (725818) [Alexa Fluor® 405] Summary

• Immunogen: E. coli-derived recombinant mouse IKKβ
  Val530-Asp757
  Accession # O88351
• Specificity: Detects mouse IKK beta in direct ELISAs and Western blots.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Activin A Antibody (725818) [Alexa Fluor® 405]

• Activin A
• activin AB alpha polypeptide
• Activin beta-A chain
• erythroid differentiation factor
• Erythroid differentiation protein
• follicle-stimulating hormone-releasing protein
• FSH-releasing protein
• inhibin beta A chain
• inhibin beta A subunit
• Inhibin, beta-1

Background

I kappa B kinase beta (IKK beta ) is also known as IKBKB and IKK2. The classical active IKK complex, composed of IKK alpha , IKK beta , and two forms of processed IKK gamma , phosphorylates and inactivates I kappa B, resulting in the release and nuclear translocation of active NF kappa B. Like IKK alpha , IKK beta contains kinase (aa 15-300), leucine zipper (aa 458‑479), and helix-loop-helix (aa 605-644) domains. NF kappa B-inducing kinase (NIK) phosphorylates and activates IKK alpha /IKK beta heterodimers. Within amino acids 530‑757, mouse IKKb shares 89% and 96% aa sequence identity with human and rat IKKb, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.