IKK beta Antibody (725818) [Alexa Fluor™ Plus 594]

• Reactivity: Mu
• Clone: 725818
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor Plus 594

IKK beta Antibody (725818) [Alexa Fluor™ Plus 594] Summary

• Specificity: Detects mouse IKK beta in direct ELISAs and Western blots.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IKK beta Antibody (725818) [Alexa Fluor™ Plus 594]

• EC 2.7.11
• EC 2.7.11.10
• I-kappa-B kinase 2
• I-kappa-B-kinase beta
• IkBKB
• IKK beta
• IKK2
• IKK2FLJ38368
• IKK-B
• IKK-betaFLJ36218
• IKKBFLJ40509
• inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
• inhibitor of nuclear factor kappa-B kinase subunit beta
• MGC131801
• NFKBIKB
• NFKBIKBFLJ33771
• Nuclear factor NF-kappa-B inhibitor kinase beta

Background

I kappa B kinase beta (IKK beta ) is also known as IKBKB and IKK2. The classical active IKK complex, composed of IKK alpha , IKK beta , and two forms of processed IKK gamma , phosphorylates and inactivates I kappa B, resulting in the release and nuclear translocation of active NF kappa B. Like IKK alpha , IKK beta contains kinase (aa 15-300), leucine zipper (aa 458‑479), and helix-loop-helix (aa 605-644) domains. NF kappa B-inducing kinase (NIK) phosphorylates and activates IKK alpha /IKK beta heterodimers. Within amino acids 530‑757, mouse IKKb shares 89% and 96% aa sequence identity with human and rat IKKb, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.