Activin A Products

Description

Position of the Chimera RNAi. The related RNAi products listed were designed from different accesion number but sharing the same RNAi sequence. Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Bioinformatics

Product By Gene ID	3624
Alternate Names	Activin A activin AB alpha polypeptide Activin beta-A chain erythroid differentiation factor Erythroid differentiation protein follicle-stimulating hormone-releasing protein FSH-releasing protein inhibin beta A chain inhibin beta A subunit Inhibin, beta-1

Research Areas for Activin A

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Stem Cell Signaling Pathway

Related Activin A Blog Posts

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Transforming Growth Factor beta Signaling in Stem Cells Transforming growth factor beta (TGF beta) signaling along with its family members have been implicated in development and maintenance of various organs. Stem cells are important contributors to this process and are characterized by their ability to s...    Read more.

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