Aconitase 2 Antibody (1A11)

Product Discontinued

Aconitase 2 Antibody (1A11) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: ACO2 (AAH14092, 1 a.a. ~ 179 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAPYSLLVTRLQKALGVRQYHVASVLCQRAKVAMSHFEPNEYIHYDLLEKNINIVRKRLNRPLTLSEKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQFISSGLSKVAVPSTIHCDHLIEAQVGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWKPGSGIIHQIILE
• Specificity: aconitase 2, mitochondrial
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: ACO2
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunoprecipitation
• Application Notes: Antibody reactivity against recombinant protein on ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Aconitase 2 Antibody (1A11)

• aconitase 2, mitochondrial
• Aconitase
• aconitate hydratase, mitochondrial
• ACONM
• Citrate hydro-lyase
• EC 4.2.1
• EC 4.2.1.3
• MGC20605
• MGC33908

Background

The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Aconitase 2 Antibody (H00000050-M01)(1)

Publication using H00000050-M01

• Lin G, Brownsey RW, MacLeod KM. Regulation of mitochondrial aconitase by phosphorylation in diabetic rat heart. Cell Mol Life Sci. 2009-03-01 [PMID: 19153662]

Bioinformatics

• Gene Symbol: ACO2
• Entrez:
  • 50(Human)
• OMIM:
  • 100850(Human)
• Uniprot:
  • AAH14092(Human)