Acetylcholinesterase/ACHE Assay Kit (Fluorometric)

Acetylcholinesterase/ACHE Assay Kit (Fluorometric) [KA4131] - The standard curve is for the purpose of demonstration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.

• Applications: Func
• Suitable Sample Type: Biological Samples
• Standard Curve Range: 0.1 mU/ml to 100 mU/ml
• Sensitivity: 0.01 mU

Acetylcholinesterase/ACHE Assay Kit (Fluorometric) Summary

• Description: Quality control test: Standard curve This kit uses our outstanding Thiolite Green to quantify the thiocholine produced from the hydrolysis of acetylthiocholine by AChE in blood, in cell extracts, and in other solutions. Thiolite Green is not fluorescent until reacted with a thiol group. It has spectral properties similar to those of fluorescein, making this assay compatible with almost every fluorescence instrument.
• Specificity: Acetylcholinesterase Assay Kit (Green Fluorescence) is a one-step fluorometric assay for the detection of AChE activity. Excitation (Max): 490 nm, Emission (Max): 520 nm.
• Standard Curve Range: 0.1 mU/ml to 100 mU/ml
• Sensitivity: 0.01 mU
• Assay Type: Fluorometric
• Sample Volume: 50 ul
• Kit Type: Assay Kit (Fluorometric)
• Gene: ACHE

Applications/Dilutions

• Dilutions:
  • Functional

Packaging, Storage & Formulations

• Storage: Store at -20C.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Acetylcholinesterase/ACHE Assay Kit (Fluorometric)

• acetylcholinesterase (Yt blood group)
• Acetylcholinesterase
• ACHE
• apoptosis-related acetylcholinesterase
• ARACHE
• EC 3.1.1
• EC 3.1.1.7
• N-ACHE
• Yt blood group
• YT

Background

Acetylcholinesterase (AChE) is one of the most crucial enzymes for nerve response and function. AChE degrades the neurotransmitter acetylcholine (ACh) into choline and acetic acid. It is mainly found at neuromuscular junctions and cholinergic synapses in the central nervous system, where its activity serves to terminate the synaptic transmission. AChE inhibitors are among the key drugs approved for Alzheimer's disease (AD) and myasthenia gravis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: ACHE