Acetylcholinesterase/ACHE Products

Description

Position of the Chimera RNAi. The related RNAi products listed were designed from different accesion number but sharing the same RNAi sequence. Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene. The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo. Chimera RNAi has many advantages over the conventional siRNAs. First, it has been demonstrated to have reliable knock-down for over 10,000 human genes. Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence. Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Bioinformatics

Product By Gene ID	43
Alternate Names	acetylcholinesterase (Yt blood group) Acetylcholinesterase ACHE apoptosis-related acetylcholinesterase ARACHE EC 3.1.1 EC 3.1.1.7 N-ACHE Yt blood group YT

Research Areas for Acetylcholinesterase/ACHE

Find related products by research area and learn more about each of the different research areas below.

Neuronal Cell Markers
Neuroscience
Neurotransmission

Related Acetylcholinesterase/ACHE Blog Posts

Check out the latest blog posts on Acetylcholinesterase/ACHE.

HIV-associated neurocognitive disorders involve extracellular Nef-induced modification of lipid rafts and redistribution of Alzheimer’s disease-related proteins Jamshed Arslan, Pharm D, PhD Cholesterol is an essential part of animal cell membranes. Cholesterol-rich lipid rafts maintain the fluidity and protein trafficking of plasma membranes. Cellular ABCA1 protein moves cho...    Read more.

Read more Acetylcholinesterase/ACHE related blogs.