Acetylcholinesterase/ACHE Products

Description

Cholinergic neurotransmission occurs in motor, autonomic and central nervous synapses and requires very rapid inactivation of its transmitter, acetylcholine (ACh). Acetylcholinesterase (AChE) rapidly hydrolyzes ACh to acetate and choline, thereby inactivating it. AChE is found in the neuromuscular junction anchored to the basal lamina which runs between the nerve terminal and muscle membrane. AChE is also found outside the nervous and neuromuscular system in blood, lymph, germ and liver cells suggesting a role for AChE not related to cholinergic transmission. Another less specific cholinesterase, butyrylcholinesterase (BChE), seems to contribute to the regulation of the ACh concentration in the synaptic cleft.

Bioinformatics

Entrez	11423 Mouse 43 Human 83817 Rat
Uniprot	NM_015831 Human NP_000656 Human NP_000656. Human NP_000656.1 Human P22303 Human
Product By Gene ID	43
Alternate Names	acetylcholinesterase (Yt blood group) acetylcholinesterase AChE apoptosis-related acetylcholinesterase ARACHE EC 3.1.1 EC 3.1.1.7 N-ACHE Yt blood group YT

Research Areas for Acetylcholinesterase/ACHE

Find related products by research area and learn more about each of the different research areas below.

Cellular Markers
Neuronal Cell Markers
Neuroscience
Neurotransmission

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