Immunohistochemistry-Paraffin: Acetylcholinesterase/ACHE Antibody [NBP1-51274] - Analyzes of AChE (K585) pAb bin paraffin-embedded human rectum carcinoma tissue at 1:50,showing membrnae and nuclear staining.Negative ...read more
Western Blot: Acetylcholinesterase/ACHE Antibody [NBP1-51274] - Analysis of AChE (K585) pAb in extracts from Jurkat cells.
Immunohistochemistry-Paraffin: Acetylcholinesterase/ACHE Antibody [NBP1-51274] - Analyzes of AChE (K585) pAb bin paraffin-embedded human lung carcinoma tissue at 1:50,showing membrnae and nuclear staining.Negative ...read more
Immunocytochemistry/Immunofluorescence was reported in scientific literature.
70 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2)
0.05% Sodium Azide
Immunogen affinity purified
Alternate Names for Acetylcholinesterase/ACHE Antibody
acetylcholinesterase (Yt blood group)
Yt blood group
Acetylcholinesterase (AChE) hydrolyzes acetylcholine at synaptic junctions.Alternative mRNA splicing gives rise to three forms of AChE. The T form, also known as the asymmetric form, is soluble and is present in synapses. The H form is also known as the globular form and is present on the outer surfaces of cell membranes. The R form is not known to be a functional species. AChE globular form subunits are GPI-anchored to cell membranes and asymmetric subunits are anchored to basal lamina components by a collagen tail. The catalytic subunits of AChE are oligomers composed of disulfide-linked homodimers.The loss of AChE from cholinergic and noncholinergic neurons in the brain is seen in patients with Alzheimer's disease. However, AChE activity is increased around amyloid plaques, which may be due to a disturbance in calcium homeostasis involving the opening of L-type voltage-dependent calcium channels.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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