Acetylcholinesterase/ACHE Antibody

Images

 
Western Blot: Acetylcholinesterase/ACHE Antibody [NBP1-51274] - Lane1:Hela whole cell lysate. Lane2:HEK239T whole cell lysate. Lane3:Mouse liver tissue lysate. Lane4:Rat kidney tissue lysate.
Immunohistochemistry-Paraffin: Acetylcholinesterase/ACHE Antibody [NBP1-51274] - Analyzes of AChE (K585) pAb bin paraffin-embedded human rectum carcinoma tissue at 1:50,showing membrnae and nuclear staining.Negative ...read more
Western Blot: Acetylcholinesterase/ACHE Antibody [NBP1-51274] - Analysis of AChE (K585) pAb in extracts from Jurkat cells.
Immunohistochemistry-Paraffin: Acetylcholinesterase/ACHE Antibody [NBP1-51274] - Analyzes of AChE (K585) pAb bin paraffin-embedded human lung carcinoma tissue at 1:50,showing membrnae and nuclear staining.Negative ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-51274
    • Availability
      Product Discontinued

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Acetylcholinesterase/ACHE Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 560-600 of Human AChE.
Marker
Early Neuronal Development Marker
Clonality
Polyclonal
Host
Rabbit
Gene
ACHE
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Immunocytochemistry/Immunofluorescence was reported in scientific literature.
Theoretical MW
70 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publications using
NBP1-51274 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Acetylcholinesterase/ACHE Antibody

  • acetylcholinesterase (Yt blood group)
  • Acetylcholinesterase
  • ACHE
  • apoptosis-related acetylcholinesterase
  • ARACHE
  • EC 3.1.1
  • EC 3.1.1.7
  • N-ACHE
  • Yt blood group
  • YT

Background

Acetylcholinesterase (AChE) hydrolyzes acetylcholine at synaptic junctions.Alternative mRNA splicing gives rise to three forms of AChE. The T form, also known as the asymmetric form, is soluble and is present in synapses. The H form is also known as the globular form and is present on the outer surfaces of cell membranes. The R form is not known to be a functional species. AChE globular form subunits are GPI-anchored to cell membranes and asymmetric subunits are anchored to basal lamina components by a collagen tail. The catalytic subunits of AChE are oligomers composed of disulfide-linked homodimers.The loss of AChE from cholinergic and noncholinergic neurons in the brain is seen in patients with Alzheimer's disease. However, AChE activity is increased around amyloid plaques, which may be due to a disturbance in calcium homeostasis involving the opening of L-type voltage-dependent calcium channels.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Acetylcholinesterase/ACHE Antibody (NBP1-51274)(3)

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics Tool for Acetylcholinesterase/ACHE Antibody (NBP1-51274)

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Bioinformatics

Gene Symbol ACHE
Entrez
Uniprot