ABCG4 Antibody

Western Blot: ABCG4 Antibody [NBP2-15229] - Sample (30 ug of whole cell lysate) A: MCF-7 7.5% SDS PAGE; antibody diluted at 1:5000.

Product Discontinued

ABCG4 Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human ABCG4. The exact sequence is proprietary.
• Localization: Membrane
• Predicted Species: Mouse (100%), Rat (99%), Bovine (91%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ABCG4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:1000-1:10000
• Theoretical MW: 72 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Immunogen affinity purified

Alternate Names for ABCG4 Antibody

• ATP-binding cassette, sub-family G (WHITE), member 4
• ATP-binding cassette, subfamily G, member 4
• putative ABC transporter
• WHITE2ATP-binding cassette sub-family G member 4

Background

The protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily and is expressed predominantly in liver tissue. The function has not yet been determined but may involve cholesterol transport. Alternate splice variants have been described but their full length sequences have not been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for ABCG4 Antibody (NBP2-15229)(2)

Publications using NBP2-15229

• Cipollari, E, Szapary, H J Et al. Correlates and Predictors of Cerebrospinal Fluid Cholesterol Efflux Capacity from Neural Cells, a Family of Biomarkers for Cholesterol Epidemiology in Alzheimer's Disease. J Alzheimers Dis 2020-02-18 [PMID: 32065798] (ICC/IF, Human)
• Dafnis I, Raftopoulou C, Mountaki C et al. ApoE isoforms and carboxyl-terminal-truncated apoE4 forms affect neuronal BACE1 levels and AB production independently of their cholesterol efflux capacity Biochem. J. 2018-05-31 [PMID: 29743204] (WB)

Review for ABCG4 Antibody (NBP2-15229) (1)

Average Rating: 5

(Based on 1 review)

We have 1 review tested in 1 species: Human.

reviewed by: Angeliki Chroni WB Human 10/08/2014

Summary

• Application: Western Blot
• Sample Tested: ABCG4-transfected HEK293 whole cell lysate and controls (untransfected cells)
• Species: Human

Bioinformatics

• Gene Symbol: ABCG4
• Uniprot:
  • Q9H172(Human)