ABCG2/CD338 Antibody (MM0047-2J39)

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Immunohistochemistry-Paraffin: ABCG2 Antibody (MM0047-2J39) [NB110-93511] - Normal Human Placenta Tissue

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, IHC-P, CyTOF-ready
Clone
MM0047-2J39
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

ABCG2/CD338 Antibody (MM0047-2J39) Summary

Immunogen
human recombinant rHABCG2 protein
Marker
Stem Cell Marker
Specificity
This was selected for its ability to detect human ABCG2 by flow cytometry and immunocytochemistry.
Isotype
IgG2
Clonality
Monoclonal
Host
Mouse
Gene
ABCG2
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:100-1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:100-1000
  • CyTOF-ready
Positive Control
ABCG2/CD338 Lysate (NBL1-07187)

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
A 0.2 um filtered solution in PBS
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein G purified
Reconstitution Instructions
Reconstitute with 0.5 ml sterilized PBS to a final concentration of 0.2 mg/ml.

Alternate Names for ABCG2/CD338 Antibody (MM0047-2J39)

  • ABC transporter
  • ABC15
  • ABCG2
  • ABCP
  • ABCPMGC102821
  • ATP-binding cassette sub-family G member 2
  • ATP-binding cassette transporter G2
  • ATP-binding cassette, sub-family G (WHITE), member 2
  • BCRP
  • BCRP1
  • BCRPMRX
  • BMDP
  • Breast cancer resistance protein
  • CD338 antigen
  • CD338
  • CDw338
  • EST157481
  • mitoxantrone resistance protein
  • Mitoxantrone resistance-associated protein
  • MXR
  • MXRMXR1
  • placenta specific MDR protein
  • Placenta-specific ATP-binding cassette transporter

Background

An ABC transporter. Allows efflux of Hoechst dye, a property that has been used to separate bone marrow side population cells, which express BCRP/ABCG2. Appears to play a major role in the multidrug resistance phenotype of a specific MCF-7 breast cancer cell line. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for ABCG2/CD338 Antibody (NB110-93511) (0)

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NB110-93511AF405
Alexa Fluor 488 Labeled NB110-93511AF488
Alexa Fluor 647 Labeled NB110-93511AF647
Alexa Fluor 700 Labeled NB110-93511AF700
Allophycocyanin Labeled NB110-93511APC
DyLight 350 Labeled NB110-93511UV
DyLight 405 Labeled NB110-93511V
DyLight 488 Labeled NB110-93511G
DyLight 680 Labeled NB110-93511FR
DyLight 755 Labeled NB110-93511IR
PE Labeled NB110-93511PE
PerCP Labeled NB110-93511PCP

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Bioinformatics

Gene Symbol ABCG2
Entrez