ABCG2/CD338 Products

Antibodies
ABCG2/CD338 Antibody (3G8)
ABCG2/CD338 Antibody (3G8)
NBP2-22124
Species: Hu, Mu, Pm
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
ABCG2/CD338 Antibody (BXP-21) ...
ABCG2/CD338 Antibody (BXP-21)
NB100-2177
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Mouse Monoclonal
ABCG2/CD338 Antibody (5D3)
ABCG2/CD338 Antibody (5D3)
MAB995
Species: Hu
Applications: Flow, ICC
Host: Mouse Monoclonal
Lysates
ABCG2/CD338 Overexpression Ly ...
ABCG2/CD338 Overexpression Lysate ...
H00009429-T01
Species: Hu
Applications: WB
ABCG2/CD338 Overexpression Ly ...
ABCG2/CD338 Overexpression Lysate ...
NBL1-07187
Applications: WB
Proteins
ABCG2/CD338 Partial Recombina ...
ABCG2/CD338 Partial Recombinant Pr...
H00009429-Q02
Species: Hu
Applications: WB, ELISA, PA
ABCG2/CD338 Partial Recombina ...
ABCG2/CD338 Partial Recombinant Pr...
H00009429-Q01
Species: Hu
Applications: WB, ELISA, PA
ABCG2/CD338 Recombinant Prote ...
ABCG2/CD338 Recombinant Protein
H00009429-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
ABCG2/CD338 RNAi
ABCG2/CD338 RNAi
H00009429-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Tumor cells may display a multidrug resistant phenotype by overexpression of ATP-binding cassette transporters such as multidrug resistance (MDRI) p-glycoprotein, multidrug resistance protein 1 (MRP1), and breast cancer resistance protein (BCRP). Tumor cells can be intrinsically resistant to drugs or they can acquire resistance to structurally and functionally unrelated drugs on drug exposure. This phenomenon is known as multidrug resistance (MDR). In human tumor cells, several transporter proteins can be involved in MDR. These proteins, MDR1 P-gp (ABCB1), MRP1 (ABCC1), MRP2 (ABCC2), MRP3 (ABCC3), and BCRP (ABCG2), belong to the ABC transporter family. They act as efflux pumps, which result in decreased intracellular concentrations of cytotoxic drugs. BCRP is a recently discovered half-transporter that probably acts as a homo- or heterodimer in transporting cytotoxic agents. The transporter molecule is capable of transporting several anticancer drugs but has thus far been found mainly in MX-resistant cell lines.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Mouse
Product By Gene ID 9429
Alternate Names
  • ABC15
  • CD338 antigen
  • CDw338
  • placenta specific MDR protein
  • BCRP1
  • mitoxantrone resistance protein
  • Placenta-specific ATP-binding cassette transporter
  • ATP-binding cassette transporter G2
  • Mitoxantrone resistance-associated protein
  • ATP-binding cassette sub-family G member 2
  • Breast cancer resistance protein
  • ABC transporter
  • EST157481
  • CD338
  • MXRMXR1
  • BCRPMRX
  • ABCPMGC102821
  • BMDP
  • ATP-binding cassette, sub-family G (WHITE), member 2

Research Areas for ABCG2/CD338

Find related products by research area and learn more about each of the different research areas below.

ABC Transporters
Cancer
Cellular Markers
Hematopoietic Stem Cell Markers
Neuronal Cell Markers
Neuronal Stem Cell Markers
Stem Cell Markers

Bioinformatics Tool for ABCG2/CD338

Discover related pathways, diseases and genes to ABCG2/CD338. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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