Human ABCC5 ELISA Kit (Colorimetric)

ELISA: Human ABCC5 ELISA Kit (Colorimetric) [NBP2-66377] - Samples were spiked with high concentrations of Human ABCC5 and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

ELISA: Human ABCC5 ELISA Kit (Colorimetric) [NBP2-66377] - Standard Curve Reference

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, plasma and other biological fluids
• Standard Curve Range: 78.13 - 5000 pg/mL
• Sensitivity: 46.88 pg/mL

Human ABCC5 ELISA Kit (Colorimetric) Summary

• Specificity: This kit recognizes Human ABCC5 in samples. No significant cross-reactivity or interference between Human ABCC5 and analogues was observed.
• Standard Curve Range: 78.13 - 5000 pg/mL
• Sensitivity: 46.88 pg/mL
• Assay Type: Sandwich-ELISA
• Inter-Assay: CV% < 5.79%
• Intra-Assay: CV% < 4.65%
• Spike Recovery: 86-106%
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: ABCC5

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human ABCC5 ELISA Kit (Colorimetric)

• ABCC5
• ATP-binding cassette sub-family C member 5
• ATP-binding cassette, sub-family C (CFTR/MRP), member 5
• canalicular multispecific organic anion transporter C
• EC 7.6.2.-
• EC 7.6.2.2
• EST277145
• MOAT-C
• MOAT-CABC33
• MRP5
• MRP5MOATC
• multidrug resistance-associated protein 5
• Multi-specific organic anion transporter C
• pABC11
• SMRP
• SMRPDKFZp686C1782

Background

ABCC5 is encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected; however, the complete sequence and translation initiation site is unclear. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: ABCC5