Human ABCC5 ELISA Kit (Colorimetric)

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Human ABCC5 ELISA Kit (Colorimetric) [NBP2-66377] - Standard Curve Reference

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Suitable Sample Type
Serum, plasma and other biological fluids.
Standard Curve Range
78.13 - 5000 pg/mL
Sensitivity
46.88 pg/mL

Order Details

Human ABCC5 ELISA Kit (Colorimetric) Summary

Specificity
This kit recognizes Human ABCC5 in samples. No significant cross-reactivity or interference between Human ABCC5 and analogues was observed.
Standard Curve Range
78.13 - 5000 pg/mL
Sensitivity
46.88 pg/mL
Assay Type
Sandwich-ELISA
Inter-Assay
CV% < 5.79%
Intra-Assay
CV% < 4.65%
Spike Recovery
86-106%
Sample Volume
100 uL
Kit Type
ELISA Kit (Colorimetric)
Gene
ABCC5

Applications/Dilutions

Dilutions
  • ELISA

Packaging, Storage & Formulations

Storage
Storage of components varies. See protocol for specific instructions.

Kit Components

Components
  1. Biotinylated Detection Ab Diluent
  2. Certificate of Analysis
  3. Concentrated Biotinylated Detection Ab (100×)
  4. Concentrated HRP Conjugate (100×)
  5. Concentrated Wash Buffer (25×)
  6. HRP Conjugate Diluent
  7. Micro ELISA Plate(Dismountable)
  8. Plate Sealer
  9. Product Description
  10. Reference Standard & Sample Diluent
  11. Reference Standard
  12. Stop Solution
  13. Substrate Reagent

Alternate Names for Human ABCC5 ELISA Kit (Colorimetric)

  • ABCC5
  • ATP-binding cassette sub-family C member 5
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 5
  • canalicular multispecific organic anion transporter C
  • EC 7.6.2.-
  • EC 7.6.2.2
  • EST277145
  • MOAT-C
  • MOAT-CABC33
  • MRP5
  • MRP5MOATC
  • multidrug resistance-associated protein 5
  • Multi-specific organic anion transporter C
  • pABC11
  • SMRP
  • SMRPDKFZp686C1782

Background

ABCC5 is encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected; however, the complete sequence and translation initiation site is unclear. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol ABCC5