ABCA8 Antibody

• Reactivity: Hu
• Applications: ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

ABCA8 Antibody Summary

• Description: Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.
• Immunogen: Peptide with sequence C-KEQELGDFEEDFD corresponding to C-Terminus according to NP_009099.1.
• Epitope: C terminus
• Specificity: This antibody is expected to cross-react with the highly similar Human ABCA9, since the immunizing peptide differs from ABCA9 with only one residue (F8).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ABCA8
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:4000
• Application Notes: WB: Preliminary experiments gave an approx. 50-55 kDa band in human brain (cerebellum, cerebral cortex, frontal cortex), heart, skeletal muscle and testis lysates after 0.3 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 179 kDa band according to NP_009099.1. The 50-55 kDa band was successfully blocked by incubation with the immunizing peptide.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for ABCA8 Antibody

• ATP-binding cassette sub-family A member 8
• ATP-binding cassette, sub-family A (ABC1), member 8
• EC 3.6.3
• EC 3.6.3.41
• KIAA0822MGC163152

Background

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The function of this protein has not yet been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ABCA8 Antibody (NBP1-20867)(1)

Publication using NBP1-20867

• Tsuruoka S, Ishibashi K, Yamamoto H et al. Functional analysis of ABCA8, a new drug transporter. Biochem Biophys Res Commun 2002-10-18 [PMID: 12379217]

Bioinformatics

• Gene Symbol: ABCA8
• Entrez:
  • 10351(Human)
• Uniprot:
  • NP_009099.1(Human)