Recombinant Human 4-1BB Ligand/TNFSF9 Protein

Product Discontinued

Recombinant Human 4-1BB Ligand/TNFSF9 Protein Summary

• Description: Recombinant bioactive protein containing 185 amino acids for Human 4-1BB Ligand/TNFSF9
  
  

  Source:E. coli
  Amino Acid Sequence:(P41273)

• Preparation Method: Determined to be >98% pure by SDS-PAGE
• Details of Functionality: Determined by the dose-dependent stimulation of IL-8 production by human PBMC. The ED50 for the effect is less than 10 ng/ml. Please note: results may vary with PBMC donors.
• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: TNFSF9
• Purity: >98%, by SDS-PAGE
• Endotoxin Note: <0.1 ng/ug

Applications/Dilutions

• Dilutions:
  • Bioactivity
  • SDS-Page
• Theoretical MW: 19.5 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from 5 mM Tris (pH 8.0), 75 mM NaCl.
• Concentration: Lyoph
• Purity: >98%, by SDS-PAGE
• Reconstitution Instructions: Reconstitute in H2O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4C for 1 week or -20C for long-term storage.

Alternate Names for Recombinant Human 4-1BB Ligand/TNFSF9 Protein

• 41BB Ligand
• 4-1BB Ligand
• 4-1BBL
• 4-1BB-L
• CD137L
• homolog of mouse 4-1BB-L
• receptor 4-1BB ligand
• TNFSF9
• tumor necrosis factor (ligand) superfamily, member 9
• tumor necrosis factor ligand superfamily member 9

Background

Human 4-1BB Ligand (4-1BBL) is a member of the emerging family of Ligands with structural homology to tumor necrosis factor. Recombinant human 4-1BBL is a 19.5 kDa protein containing 185 amino acid residues, comprising the TNF-like extra-Cellular domain of 4-1BBL.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: TNFSF9