Recombinant Human 2B4/CD244/SLAMF4 Protein

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SDS-Page: Recombinant Human 2B4/CD244/SLAMF4 Protein [NBP1-98875] - 15% SDS-PAGE (3ug)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.5 mg/ml

Order Details

Recombinant Human 2B4/CD244/SLAMF4 Protein Summary

Description
A denatured recombinant protein with a His-tag corresponding to amino acids 19 to 224 of Human 2B4/CD244/SLAMF4

Source: E. coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHGKGCQG SADHVVSISG VPLQLQPNSI QTKVDSIAWK KLLPSQNGFH HILKWENGSL PSNTSNDRFS FIVKNLSLLI KAAQQQDSGL YCLEVTSISG KVQTATFQVF VFDKVEKPRL QGQGKILDRG RCQVALSCLV SRDGNVSYAW YRGSKLIQTA GNLTYLDEEV DINGTHTYTC NVSNPVSWES HTLNLTQDCQ NAHQEFRFWP
Protein/Peptide Type
Recombinant Protein
Gene
CD244
Purity
>85%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
25.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl buffer, pH8.0, 0.4M urea
Concentration
0.5 mg/ml
Purity
>85%, by SDS-PAGE

Notes

The purity of this protein is > 85% by SDS - PAGE.

Alternate Names for Recombinant Human 2B4/CD244/SLAMF4 Protein

  • 2B4
  • CD244 antigen
  • CD244 molecule, natural killer cell receptor 2B4
  • CD244
  • h2B4
  • NAIL
  • NAILNK cell activation-inducing ligand
  • natural killer cell receptor 2B4
  • NKR2B4
  • NKR2B4NK cell type I receptor protein 2B4,2B4CD244 natural killer cell receptor 2B4
  • Nmrk
  • SLAMF4
  • SLAMF4NK cell activation inducing ligand NAIL

Background

CD244 (Natural Killer Cell Receptor 2B4), also known as Cluster of Differentiation 244, contains 2 Ig-like (immunoglobulin-like) domains. A role for the subtypes of CD2 Ig superfamily receptors has been recently demonstrated in eosinophilic inflammation in experimental asthma and atopic asthmatics. Functions of CD244 molecules are in eosinophil adhesion and chemotaxis, and correlated the results to the pathophysiology of allergic rhinitis (AR). The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Recombinant human CD244 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol CD244
Entrez
Uniprot

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