Human 15-PGDH/HPGD ELISA Kit (Colorimetric)

ELISA: Human 15-PGDH/HPGD ELISA Kit (Colorimetric) [NBP2-80340] - Example standard curve for Human 15-PGDH/HPGD ELISA Kit (Colorimetric). These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

• Reactivity: Hu
• Applications: ELISA
• Conjugate: HRP
• Suitable Sample Type: Lysate
• Standard Curve Range: 54.69-3500 pg/ml (example only; lot dependent)
• Sensitivity: 19.2 pg/ml

Human 15-PGDH/HPGD ELISA Kit (Colorimetric) Summary

• Specificity: Recognizes both recombinant and natural Human 15-PGDH/HPGD.
• Standard Curve Range: 54.69-3500 pg/ml (example only; lot dependent)
• Sensitivity: 19.2 pg/ml
• Assay Type: Sandwich ELISA
• Inter-Assay: CV% < 9.5 %
• Intra-Assay: CV% < 3.2
• Sample Volume: 100 ul
• Kit Type: ELISA Kit (Colorimetric)
• Gene: HPGD

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

• Storage: Storage is content dependent.

Alternate Names for Human 15-PGDH/HPGD ELISA Kit (Colorimetric)

• 15-hydroxyprostaglandin dehydrogenase [NAD+]
• 15PGDH
• 15-PGDH
• EC 1.1.1
• EC 1.1.1.141
• HPGD
• hydroxyprostaglandin dehydrogenase 15-(NAD)
• NAD+-dependent 15-hydroxyprostaglandin dehydrogenase
• PGDH1
• PGDH1PGDH
• Prostaglandin dehydrogenase 1
• SDR36C1
• short chain dehydrogenase/reductase family 36C, member 1

Background

15-PGDH (15-hydroxyprostaglandin dehydrogenase (NAD+)) is responsible for prostaglandin inactivation and supports the regulation of functions that are controled by prostaglandin levels. Specifically, 15PGDH catalyzes the chemical reaction to convert NAD+ to NADH and H+.

15-PGDH is a novel tumor suppressor in the COX-2 pathway. 15-PGDH is found in many normal tissues and appears to be down-regulated in colorectal and lung carcinoma tissue.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: HPGD