iNOS Products

Antibodies
iNOS Antibody
iNOS Antibody
NB300-605
Species: Hu, Mu, Rt, Po, Av, Fe, Fi, Rb, Xp
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
iNOS Antibody (2D2-B2) [Uncon ...
iNOS Antibody (2D2-B2) [Unconjugated]
MAB9502
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
Kits
iNOS Colorimetric Assay Kit
iNOS Colorimetric Assay Kit
KA1634
Applications: Func
Lysates
iNOS Overexpression Lysate (N ...
iNOS Overexpression Lysate (Native)
NBL1-13721
Applications: WB
Proteins
iNOS Partial Recombinant Prot ...
iNOS Partial Recombinant Protein
H00004843-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
iNOS RNAi
iNOS RNAi
H00004843-R01
Species: Hu
Applications: RNAi, RNAi SP
iNOS RNAi
iNOS RNAi
H00004843-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Nitric oxide (NO) is an inorganic, gaseous free radical that carries a variety of messages between cells. Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO. NO production is mediated by members of the nitric oxide synthase (NOS) family. NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO. Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) & endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned. All NOS isoforms contain calmodulin, nicotinamide adenine dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) binding domains.eNOS synthesizes NO in vascular endothelial cells where it appears to play an important role in the control of vasotension and platelet aggregation. eNOS and bNOS share ~50% sequence homology, and their activity depends on binding to the calcium/calmodulin complex. Both constitutive isoforms respond immediately to increased levels of calcium to produce low levels of NO over a short period of time.

Bioinformatics

Entrez Human
Mouse
Rat
Bovine
Uniprot Human
Human
Mouse
Product By Gene ID 4843
Alternate Names
  • NOS, type II
  • Inducible NO synthase
  • nitric oxide synthase, macrophage
  • Hepatocyte NOS
  • nitric oxide synthase, inducible
  • iNOS
  • INOS
  • nitric oxide synthase 2A (inducible, hepatocytes)
  • EC 1.14.13.39
  • NOS
  • NOS2ANOS type II
  • HEP-NOSPeptidyl-cysteine S-nitrosylase NOS2
  • Inducible NOS
  • nitric oxide synthase 2, inducible

Research Areas for iNOS

Find related products by research area and learn more about each of the different research areas below.

Cancer
HIF Target Genes
Hypoxia
Neuroscience
Neurotransmission

Bioinformatics Tool for iNOS

Discover related pathways, diseases and genes to iNOS. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related iNOS Blog Posts

Check out the latest blog posts on iNOS.
iNOS: The Nitric Oxide Boss
Nitric oxide (NO) is an inorganic, gaseous, and reactive free radical that acts as a biologic mediator in processes such as neurotransmission, vasorelaxation, and cytotoxicity. In addition, it has antimicrobial and anti-tumoral activities. NO producti...    Read more.
Read more iNOS related blogs.