eNOS Products

Antibodies
eNOS Antibody
eNOS Antibody
NB300-500
Species: Hu, Mu, Rt, Po, Am, Bv, Ca, Dr
Applications: WB, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
eNOS Antibody [Unconjugated]
eNOS Antibody [Unconjugated]
AF950
Species: Hu
Applications: WB, Simple Western, IHC, IP
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Lysates
eNOS Overexpression Lysate (D ...
eNOS Overexpression Lysate (Denatu...
H00004846-T01
Species: Hu
Applications: WB
eNOS Overexpression Lysate (N ...
eNOS Overexpression Lysate (Native)
NBP2-10685
Applications: WB
Proteins
Recombinant Human eNOS Protei ...
Recombinant Human eNOS Protein
H00004846-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
eNOS RNAi
eNOS RNAi
H00004846-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Nitric oxide (NO) is an inorganic, gaseous free radical that carries a variety of messages between cells. Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO. NO production is mediated by members of the nitric oxide synthase (NOS) family. NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO. Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) & endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned. All NOS isoforms contain calmodulin, nicotinamide adenine dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) binding domains. iNOS is found in a variety of cell types including macrophages, hepatocytes, synoviocytes, and smooth muscle cells. Cytokines such as interferon-gamma (IFN), tumor necrosis factor (TNF), interleukin-1 and -2, and lipopolysaccarides (LPS) cause an increase in iNOS mRNA, protein, and activity levels. Protein kinase C-stimulating agents exhibit the same effect on iNOS activity. After cytokine induction, iNOS exhibits a delayed activity response which is then followed by a significant increase in NO production over a long period of time.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 4846
Alternate Names
  • endothelial
  • Endothelial NOS
  • EC 1.14.13.39
  • Constitutive NOS
  • NOS type III
  • ECNOS
  • eNOScNOS
  • NOSIII
  • nitric oxide synthase 3 (endothelial cell)

Research Areas for eNOS

Find related products by research area and learn more about each of the different research areas below.

Cancer
HIF Target Genes
Hypoxia
Neuroscience
Neurotransmission
Phospho-Specific

Bioinformatics Tool for eNOS

Discover related pathways, diseases and genes to eNOS. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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