TNF-alpha Products

Antibodies
TNF-alpha Antibody
TNF-alpha Antibody
AF-410-NA
Species: Mu
Applications: WB, CyTOF-ready, ELISA(Cap), ICC, ICFlow, Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
TNF-alpha Antibody (28401) [U ...
TNF-alpha Antibody (28401) [Unconj...
MAB610
Species: Hu
Applications: WB, ELISA(Cap), ICC, Neut
Host: Mouse Monoclonal
TNF-alpha Antibody
TNF-alpha Antibody
NBP1-19532
Species: Hu, Mu, Rt, Po, Ca, Fe, Md, Pm
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P, IHC-FrFl
Host: Rabbit Polyclonal
Antibody Pairs
TNF-alpha Antibody Pair
TNF-alpha Antibody Pair
H00007124-AP41
Species: Hu
Applications: S-ELISA
TNF-alpha Antibody Pair
TNF-alpha Antibody Pair
H00007124-AP42
Species: Hu
Applications: S-ELISA
TNF-alpha Antibody Pair
TNF-alpha Antibody Pair
H00007124-AP43
Species: Hu
Applications: S-ELISA
ELISA Kits
Human TNF-alpha ELISA Kit (Co ...
Human TNF-alpha ELISA Kit (Colorim...
NBP1-91170
Species: Hu
Applications: ELISA
Human TNF-alpha ELISA Kit (Co ...
Human TNF-alpha ELISA Kit (Colorim...
NBP1-83741
Species: Hu
Applications: ELISA
Rat TNF-alpha ELISA Kit (Colo ...
Rat TNF-alpha ELISA Kit (Colorimet...
NBP1-92681
Species: Rt
Applications: ELISA
Lysates
TNF-alpha Overexpression Lysa ...
TNF-alpha Overexpression Lysate (N...
NBL1-17134
Species: Hu
Applications: WB
Proteins
Recombinant Human TNF-alpha P ...
Recombinant Human TNF-alpha Protein
210-TA
Species: Hu
Applications: BA
Recombinant Mouse TNF-alpha ( ...
Recombinant Mouse TNF-alpha (aa 80...
410-MT
Species: Mu
Applications: BA
Recombinant Rat TNF-alpha Pro ...
Recombinant Rat TNF-alpha Protein
510-RT
Species: Rt
Applications: BA
RNAi
TNF-alpha RNAi
TNF-alpha RNAi
H00007124-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

TNF-alpha (Tumor necrosis factor, alpha), a member of the TNF ligand superfamily, is among others, secreted by macrophages, activated monocytes, neutrophils, T-cells, B-cells and natural killer cells stimulated by bacterial lipopolysaccharides. TNF-alpha shows approximately 30% homology with TNF-beta. TNF-alpha plays an important role in the regulation of immune cells. TNF-alpha has many biological activities, including a cytotoxic effect to various tumor cells, causes inflammation, cellular proliferation and plays a critical role in mediating resistance to bacterial infections. Human and murine TNF-alpha show approximately 79% homology and human TNF-alpha is active on murine cells with a slightly reduced specific activity.

Bioinformatics

Entrez Human
Mouse
Rat
Rat
Rabbit
Uniprot Human
Human
Human
Human
Human
Human
Mouse
Mouse
Rat
Product By Gene ID 7124
Alternate Names
  • Cachectin
  • tumor necrosis factor (TNF superfamily, member 2)
  • tumor necrosis factor-alpha
  • TNF-a
  • tumor necrosis factor alpha
  • Tumor necrosis factor ligand superfamily member 2
  • TNF, monocyte-derived
  • DIF
  • TNFATNF, macrophage-derived
  • TNFSF2TNF superfamily, member 2
  • TNF-alphacachectin
  • APC1 protein
  • tumor necrosis factor

Research Areas for TNF-alpha

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Asthma
Autophagy
Biologically Active Proteins
Cancer
Cytokine Research
Diabetes Research
Immune System Diseases
Immunology
Innate Immunity

Bioinformatics Tool for TNF-alpha

Discover related pathways, diseases and genes to TNF-alpha. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related TNF-alpha Blog Posts

Check out the latest blog posts on TNF-alpha.
cIAP2 - balancing cell death and cell survival
The inhibitor of apoptosis proteins (IAPs) are important regulators of cell death and inflammation. The cellular inhibitor of apoptosis protein 2 (cIAP2) contains three Baculovirus IAP repeat (BIR) domains, a Ubiquitin associated (UBA) domain, and...    Read more.
CD86 - I work in tandem with CD80
CD86 belongs to the immunoglobulin superfamily of proteins that drive innate and adaptive immune responses. It is an 80kD co-stimulatory molecule for the priming and activation of naive and memory T-cells, respectively. CD86 is expressed on activated...    Read more.
Read more TNF-alpha related blogs.