TNF-alpha Products

Antibodies
TNF-alpha Antibody (45418R) [ ...
TNF-alpha Antibody (45418R) [Uncon...
MAB510R
Species: Rt
Applications: ELISA(Cap), Neut
Host: Mouse Monoclonal
TNF-alpha Antibody (6401R) [U ...
TNF-alpha Antibody (6401R) [Unconj...
MAB2101R
Species: Hu
Applications: ICC, Neut
Host: Mouse Monoclonal
TNF-alpha Antibody (28401R) [ ...
TNF-alpha Antibody (28401R) [Uncon...
MAB610R
Species: Hu
Applications: ELISA(Cap), Neut
Host: Mouse Monoclonal
Antibody Pairs
TNF-alpha Antibody Pair
TNF-alpha Antibody Pair
H00007124-AP41
Species: Hu
Applications: S-ELISA
TNF-alpha Antibody Pair
TNF-alpha Antibody Pair
H00007124-AP42
Species: Hu
Applications: S-ELISA
TNF-alpha Antibody Pair
TNF-alpha Antibody Pair
H00007124-AP43
Species: Hu
Applications: S-ELISA
ELISA Kits
TNF-alpha ELISA Kit
TNF-alpha ELISA Kit
NBP1-91170
Species: Hu
Applications: ELISA
TNF-alpha ELISA Kit [Biotin]
TNF-alpha ELISA Kit [Biotin]
KA1823
Species: Po
TNF-alpha ELISA Kit
TNF-alpha ELISA Kit
NBP2-31085
Species: Mu
Applications: ELISA
Lysates
TNF-alpha Overexpression Lysa ...
TNF-alpha Overexpression Lysate (N...
NBL1-17134
Applications: WB
Proteins
Human TNF-alpha Protein
Human TNF-alpha Protein
NBP2-35076
Species: Hu
Applications: Func, PAGE
Human TNF-alpha His (N-Term) ...
Human TNF-alpha His (N-Term) Protein
NBP2-35078
Species: Hu
Applications: Func, PAGE
Mouse TNF-alpha Protein
Mouse TNF-alpha Protein
NBP2-35185
Species: Mu
Applications: Func, PAGE
RNAi
TNF-alpha RNAi
TNF-alpha RNAi
H00007124-R01
Species: Hu

Description

TNF-alpha (Tumor necrosis factor, alpha), a member of the TNF ligand superfamily, is among others, secreted by macrophages, activated monocytes, neutrophils, T-cells, B-cells and natural killer cells stimulated by bacterial lipopolysaccharides. TNF-alpha shows approximately 30% homology with TNF-beta. TNF-alpha plays an important role in the regulation of immune cells. TNF-alpha has many biological activities, including a cytotoxic effect to various tumor cells, causes inflammation, cellular proliferation and plays a critical role in mediating resistance to bacterial infections. Human and murine TNF-alpha show approximately 79% homology and human TNF-alpha is active on murine cells with a slightly reduced specific activity.

Bioinformatics

Entrez Human
Mouse
Rat
Rat
Rabbit
Uniprot Human
Human
Human
Human
Human
Human
Mouse
Mouse
Rat
Product By Gene ID 7124
Alternate Names
  • Cachectin
  • tumor necrosis factor (TNF superfamily, member 2)
  • tumor necrosis factor-alpha
  • TNF-a
  • tumor necrosis factor alpha
  • Tumor necrosis factor ligand superfamily member 2
  • TNF, monocyte-derived
  • DIF
  • TNFATNF, macrophage-derived
  • TNFSF2TNF superfamily, member 2
  • TNF-alphacachectin
  • APC1 protein
  • tumor necrosis factor

Research Areas for TNF-alpha

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Asthma
Autophagy
Biologically Active Proteins
Cancer
Cytokine Research
Diabetes Research
Immune System Diseases
Immunology
Innate Immunity

Bioinformatics Tool for TNF-alpha

Discover related pathways, diseases and genes to TNF-alpha. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related TNF-alpha Blog Posts

Check out the latest blog posts on TNF-alpha.
cIAP2 - balancing cell death and cell survival
The inhibitor of apoptosis proteins (IAPs) are important regulators of cell death and inflammation. The cellular inhibitor of apoptosis protein 2 (cIAP2) contains three Baculovirus IAP repeat (BIR) domains, a Ubiquitin associated (UBA) domain, and...    Read more.
CD86 - I work in tandem with CD80
CD86 belongs to the immunoglobulin superfamily of proteins that drive innate and adaptive immune responses. It is an 80kD co-stimulatory molecule for the priming and activation of naive and memory T-cells, respectively. CD86 is expressed on activated...    Read more.
Read more TNF-alpha related blogs.