Species: Hu, Mu, Rt, Gp, Bv, Ca
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC
Host: Goat Polyclonal
Species: Hu, Mu, Rt, Bt, Ca, Eq, Pm, Pm, Rb, Ch
Applications: WB, IHC, IP, ICC/IF
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Mouse Monoclonal
Species: Mu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Rt
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: Binding Activity
Species: Hu
Applications: Binding Activity
Description
NOS (nitric oxide synathase) is a mediator of NO (nitric oxide) production, an inorganic gaseous messenger between cells. In cells, NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO. Three isoforms of NOS has been identified (eNOS, iNOS, and nNOS) with all of them having binding sites for NADPH, FAD, FMN, and tetrahydrobiopterin (1). Specifically, nNOS (Neuronal nitric oxide synthase bNOS, cNOS, Type I) is bound to PSD95 located in the neuronal membrane and at increased level of Ca2+, nNOS is trasnlocated to cytoplasm. In cytoplasm, nNOS is dephosphorylated by calcineurin which initiates NO production (2). A phosphorylation by PKA and PKC on nNOS leads down-regulation of NO production.
Bioinformatics
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
4842 |
| Alternate Names |
- bNOS
- brain
- Constitutive NOS
- EC 1.14.13.39
- IHPS1
- Neuronal NOS
- nitric oxide synthase 1 (neuronal)
- N-NOS
- nNOSNOS type I
- NOS
- Peptidyl-cysteine S-nitrosylase NOS1
|
Bioinformatics Tool for nNOS
Discover related pathways, diseases and genes to nNOS. Need help? Read the
Bioinformatics Tool Guide for instructions on using this tool.
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