nNOS Products

Antibodies
nNOS Antibody
nNOS Antibody
NB100-858
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-Fr, PEP-ELISA, IHC-WhMt
Host: Goat Polyclonal
nNOS Antibody
nNOS Antibody
NB120-3511
Species: Mu, Rt, Bv, GP, Rb
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Host: Rabbit Polyclonal
Lysates
nNOS Overexpression Lysate (N ...
nNOS Overexpression Lysate (Native)
NBL1-13719
Applications: WB
Proteins
nNOS Partial Recombinant Prot ...
nNOS Partial Recombinant Protein
H00004842-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
nNOS RNAi
nNOS RNAi
H00004842-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

NOS (nitric oxide synathase) is a mediator of NO (nitric oxide) production, an inorganic gaseous messenger between cells. In cells, NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO. Three isoforms of NOS has been identified (eNOS, iNOS, and nNOS) with all of them having binding sites for NADPH, FAD, FMN, and tetrahydrobiopterin (1). Specifically, nNOS (Neuronal nitric oxide synthase bNOS, cNOS, Type I) is bound to PSD95 located in the neuronal membrane and at increased level of Ca2+, nNOS is trasnlocated to cytoplasm. In cytoplasm, nNOS is dephosphorylated by calcineurin which initiates NO production (2). A phosphorylation by PKA and PKC on nNOS leads down-regulation of NO production.

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 4842
Alternate Names
  • brain
  • N-NOS
  • NOS
  • Peptidyl-cysteine S-nitrosylase NOS1
  • IHPS1
  • Neuronal NOS
  • EC 1.14.13.39
  • Constitutive NOS
  • nNOSNOS type I
  • bNOS
  • nitric oxide synthase 1 (neuronal)

Research Areas for nNOS

Find related products by research area and learn more about each of the different research areas below.

Asthma
Cancer
HIF Target Genes
Hypoxia
Immunology
Neuroscience
Neurotransmission
Phospho-Specific

Bioinformatics Tool for nNOS

Discover related pathways, diseases and genes to nNOS. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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