XPV/DNA polymerase eta Antibody Pair

Product Discontinued

XPV/DNA polymerase eta Antibody Pair Summary

• Description: Quality control test: Immunoprecipitation-Western Blot (IP-WB). This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  
  
• Antibody pair for IP: rabbit polyclonal anti-POLH (300 ul)
• Antibody pair for WB: mouse purified polyclonal anti-POLH (50 ug)
• Clonality: Polyclonal
• Gene: POLH
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for XPV/DNA polymerase eta Antibody Pair

• DNA polymerase eta
• DNA Polymerase, eta
• EC 2.7.7.7
• POLH
• polymerase (DNA directed), eta
• RAD30 homolog A
• RAD30
• RAD30A
• RAD30AFLJ16395
• Xeroderma pigmentosum variant type protein
• XPV
• XP-V
• XPVFLJ21978

Background

DNA polymerase eta is specifically involved in DNA repair. It plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. It also plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. It targets POLI to replication foci (referenced from swissprot).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: POLH