XIAP Antibody

Product Discontinued

XIAP Antibody Summary

• Immunogen: Synthetic peptide corresponding to a portion of human ILP-2.
• Specificity: ILP-1
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: XIAP
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:100-1:2000
• Application Notes: This antibody is useful for Western Blot.
  
  The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Theoretical MW: 56.7 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

This antibody is reactive against Human

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for XIAP Antibody

• API3X-linked inhibitor of apoptosis protein
• apoptosis inhibitor 3
• baculoviral IAP repeat-containing 4
• baculoviral IAP repeat-containing protein 4
• BIRC4
• BIRC4XLP2
• E3 ubiquitin-protein ligase XIAP
• EC 6.3.2.-
• hIAP3
• hIAP-3
• hILP
• IAP3
• IAP-3
• IAP-like protein
• ILP
• ILP1
• Inhibitor of apoptosis protein 3
• MIHA
• XIAP
• X-linked IAP
• X-linked inhibitor of apoptosis

Background

The human X chromosome linked Inhibitor of Apoptosis Protein (XIAP) is a major member of the inhibitor of apoptosis (IAP) family. XIAP functions by direct binding and inhibition of several caspases, including Caspase 3, Caspase 7 and Caspase 9. During apoptosis XIAP is specifically cleaved by Caspase 3 and partially loses its function. In addition to blocking the apoptosis signaling pathway, XIAP can also bind several other proteins in the bone morphogenetic protein (BMP) signaling pathway and act as a coupler between the membrane BMP receptor and the TAB1 TAK1 complex by binding to these proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: XIAP
• Entrez:
  • 331(Human)
• Uniprot:
  • P98170()