Wnt-8b Antibody (341504) [Janelia Fluor® 549]

• Reactivity: Hu, Mu
• Applications: IHC
• Clone: 341504
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Janelia Fluor 549

Wnt-8b Antibody (341504) [Janelia Fluor® 549] Summary

• Immunogen: E. coli-derived recombinant mouse Wnt‑8b
• Specificity: Detects mouse Wnt-8b in direct ELISAs. In direct ELISAs, no cross‑reactivity with recombinant mouse Wnt-1, -2b, -3a, -4, -5a, -5b, -8a, -9b,
  -10b, recombinant human Wnt-2, -7a, -7b, or -9a is observed. Immunohistochemical staining of the human neural cell line, NTera2, demonstrates that this antibody also recognizes human Wnt-8b.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: WNT8B
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Wnt-8b Antibody (341504) [Janelia Fluor® 549]

• protein Wnt-8b
• wingless-type MMTV integration site family, member 8B
• Wnt8b
• Wnt-8b

Background

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: WNT8B