WARP/VWA1 Antibody [Alexa Fluor® 488]

• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 488

WARP/VWA1 Antibody [Alexa Fluor® 488] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse WARP isoform 1
  Arg19-Pro415
  Accession # Q8R2Z5
• Specificity: Detects mouse WARP in direct ELISAs and Western blots. In direct ELISAs, approximately 20% cross‑reactivity with recombinant human WARP is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

WARP (von Willebrand factor A [vWFA] domain-related protein) is a 50 kDa glycoprotein member of the vWFA domain superfamily of extracellular matrix proteins. It is expressed in embryonic articular cartilage, skeletal muscle and basement membranes in the PNS. WARP forms disulfide-linked homodimers and multimers, and complexes with perlecan. Secreted mouse WARP is 397 amino acids (aa) in length. It contains a vWFA domain (aa 34‑209), and two fibronectin type III domains (aa 211‑394) that likely bind to the GAG modification of perlecan. Cys369 and Cys393 contribute to intermolecular bond formation. There is one alternate start site at Met213. Mature mouse WARP (aa 19‑415) is 93% and 78% aa identical to rat and human WARP, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.