VMAT2 Antibody (CL13157) - BSA Free

Western Blot: VMAT2 Antibody (CL13157) [NBP3-18556] - Analysis in human cell line HEL.

Immunohistochemistry-Paraffin: VMAT2 Antibody (CL13157) [NBP3-18556] - Staining of human skeletal muscle shows no positivity in myocytes as expected.

Immunohistochemistry-Paraffin: VMAT2 Antibody (CL13157) [NBP3-18556] - Staining of human dorsal raphe nucleus shows strong cytoplasmic positivity in neurons.

Immunohistochemistry-Paraffin: VMAT2 Antibody (CL13157) [NBP3-18556] - Staining of human stomach shows strong cytoplasmic positivity in gastric endocrine cells.

Immunohistochemistry-Paraffin: VMAT2 Antibody (CL13157) [NBP3-18556] - Staining of human cerebral cortex shows positivity in single neural fibers, and no staining in neurons as expected.

• Reactivity: Hu, Rt
• Applications: WB, IHC
• Clone: CL13157
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

VMAT2 Antibody (CL13157) - BSA Free Summary

• Description: Novus Biologicals Mouse VMAT2 Antibody (CL13157) - BSA Free (NBP3-18556) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed using a synthetic peptide derived from Q05940, with the exact immunogen sequence remaining proprietary.
• Predicted Species: Rat (90%). Backed by our 100% Guarantee.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: SLC18A2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
  • Western Blot 1 ug/ml
• Application Notes: For use with IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Protein A purified

Alternate Names for VMAT2 Antibody (CL13157) - BSA Free

• MGC120477
• MNAT
• monoamine neurotransmitter transporter
• Monoamine transporter
• SLC18A2
• solute carrier family 18 (vesicular monoamine), member 2
• Solute carrier family 18 member 2
• SVAT
• SVMT
• SVMTMGC120478
• synaptic vesicular amine transporter
• VAT2
• VAT2MGC26538
• vesicle monoamine transporter type 2
• vesicle monoamine/H+ antiporter
• Vesicular amine transporter 2
• VMAT2

Background

VMAT2 (Vesicular amine transporter 2) acts to accumulate cytosolic monoamines into synaptic vesicles. Its function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders such as dementia with Lewy bodies. The transporter is a site of action of important drugs, including reserpine and tetrabenazine.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLC18A2