Vitronectin Native Protein

Product Discontinued

Vitronectin Native Protein Summary

• Description: Native Vitronectin
  
  

  Source:Human plasma
  Amino Acid Sequence:(P04004)

• Source: Human Plasma
• Protein/Peptide Type: Native Protein
• Gene: VTN
• Purity: >95%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 75 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from 10 mM sodium phosphate (pH 7.7).
• Concentration: Lyoph
• Purity: >95%, by SDS-PAGE
• Reconstitution Instructions: Reconstitute in H2O or aqueous buffers to a concentration no less than 0.1 mg/ml. Aliquot and store at -20C. Avoid freeze-thaw cycles.

Alternate Names for Vitronectin Native Protein

• Complement S-protein
• epibolin
• Serum Spreading Factor
• Serum-spreading factor
• Somatomedin B
• S-protein
• V75
• vitronectin (serum spreading factor, somatomedin B, complement S-protein)
• Vitronectin
• VN
• VNT
• VTN

Background

Vitronectin and plasminogen activator inhibitor type 1 are proteins that interact in the circulatory system and pericellular region to regulate fibrinolysis, cell adhesion, and migration. Plasminogen activator inhibitor type 1, a serine proteinase, through its binding to the plasma protein vitronectin, influences processes that are key regulators of hemostatic process, for example, thrombosis and wound healing. In addition, the vitronectin and plasminogen activator inhibitor type 1 complex regulates binding of blood platelets and cells to extracellular substrata in events like tumor metastasis. The plasma concentration of vitronectin is 200 to 400 ug/ml.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: VTN