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Mouse VEGFR3/Flt-4 ELISA Kit (Colorimetric)

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ELISA: Mouse VEGFR3/Flt-4 ELISA Kit (Colorimetric) [NBP2-78875] - Samples were spiked with high concentrations of Mouse VEGFR3/Flt-4 and diluted with Reference Standard & Sample Diluent to produce samples with values ...read more
ELISA: Mouse VEGFR3/Flt-4 ELISA Kit (Colorimetric) [NBP2-78875] - Standard Curve Reference

Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Suitable Sample Type
Serum, plasma, and other biological fluids
Standard Curve Range
62.50 - 4000 pg/mL
Sensitivity
37.50 pg/mL

Order Details

Mouse VEGFR3/Flt-4 ELISA Kit (Colorimetric) Summary

Specificity
This kit recognizes Mouse VEGFR3/Flt4 in samples. No Significant cross-reactivity or interference between Mouse VEGFR3/Flt4 and analogues was observed.
Standard Curve Range
62.50 - 4000 pg/mL
Sensitivity
37.50 pg/mL
Assay Type
Sandwich-ELISA
Inter-Assay
%CV < 4.39
Intra-Assay
%CV < 5.18
Spike Recovery
85 - 106%
Sample Volume
100 uL
Kit Type
ELISA Kit (Colorimetric)
Gene
FLT4

Applications/Dilutions

Dilutions
  • ELISA

Packaging, Storage & Formulations

Storage
Storage of components varies. See protocol for specific instructions.

Kit Components

Components
  1. Biotinylated Detection Ab Diluent
  2. Concentrated Biotinylated Detection Ab (100x)
  3. Concentrated HRP Conjugate (100x)
  4. Concentrated Wash Buffer (25x)
  5. HRP Conjugate Diluent
  6. Micro ELISA Plate (Dismountable)
  7. Plate Sealer
  8. Reference Standard
  9. Sample Diluent
  10. Stop Solution
  11. Substrate Reagent

Alternate Names for Mouse VEGFR3/Flt-4 ELISA Kit (Colorimetric)

  • EC 2.7.10
  • EC 2.7.10.1
  • FLT4
  • Flt-4
  • fms-related tyrosine kinase 4
  • LMPH1A
  • PCLFLT41
  • soluble VEGFR3 variant 1
  • soluble VEGFR3 variant 2
  • soluble VEGFR3 variant 3
  • Tyrosine-protein kinase receptor FLT4
  • vascular endothelial growth factor receptor 3
  • VEGF R3
  • VEGFR3
  • VEGFR-3
  • VEGFR3Fms-like tyrosine kinase 4

Background

FLT4, a VEGF Receptor type protein kinase, is an endothelial cell-specific receptor. Binding of the extracellular domain of FLT4 to the vascular endothelial growth factor-related protein VEGF-C stimulates tyrosine phosphorylation and mitogenesis of endothelial cells. FLT4 (-/-) mice have been shown to have defective blood vessel development in early embryos and to experience cardiovascular failure at embryonic day 9.5. A mutation in the FLT4 gene has been implicated in human hereditary lymphedema type I. Similarly, a mutation in the conserved catalytic domain of FLT4, in close proximity to the FLT4 mutations in human primary lymphedema, has been linked to the Chy mouse mutant.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol FLT4
Uniprot