VASP Antibody

Product Discontinued

VASP Antibody Summary

• Immunogen: Recombinant (partial), C-terminal
• Marker: Focal Adhesion Marker
• Specificity: VASP
• Clonality: Polyclonal
• Host: Rabbit
• Gene: VASP
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 mul per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
• Control:

  VASP Overexpression Lysate

Reactivity Notes

Mouse, Human.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2)
• Preservative: 0.09% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for VASP Antibody

• vasodilator-stimulated phosphoprotein
• VASP

Background

VASP (vasodilator-stimulated phosphoprotein) is a 46 kD member of the Ena/VASP family that contains WH1, EVH1, and EVH2 domains as well as GPPPPP motifs. This protein forms tetramers and may act in concert with profilin to convey signal transduction to actin filament production. VASP is a crucial factor involved in enhancement of actin filament formation and has been shown to regulatee cell motility by controlling the geometry of actin filament networks within lamellipodia. VASP can be phosphorylated by PKA and PKG; phosphorylation disrupts protein associations. VASP has been shown to interact with PKA, PKG, actin, vinculin, zyxin, profilin, F-actin, and c-abl. The Poly6156 antibody recognizes the C-terminal region of human and mouse VASP and has been shown to be useful for Western blotting.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: VASP
• Entrez:
  • 7408(Human)
  • 22323(Mouse)