UGT1A6 Antibody Summary
Recombinant fragment corresponding to a region within amino acids 8 and 227 of UGT1A6 (Uniprot ID#P19224)
Microsome, Endoplasmic reticulum membrane, Single-pass membrane protein
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7).
Immunogen affinity purified
Tested in human and mouse. Not yet tested in any other species.
Alternate Names for UGT1A6 Antibody
- GNT1UDPGT 1-6
- Phenol-metabolizing UDP-glucuronosyltransferase
- UDP glucuronosyltransferase 1 family, polypeptide A6
- UDP glycosyltransferase 1 family, polypeptide A6
- UDP-glucuronosyltransferase 1 family polypeptide A6s
- UDP-glucuronosyltransferase 1-6
- UDP-glucuronosyltransferase 1A6
- UDP-glucuronosyltransferase 1-F
- UGT1FEC 220.127.116.11
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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