UGT1A6 Antibody

Images

 
Western Blot: UGT1A6 Antibody [NBP1-33743] - A. 50 ug mouse liver lysate/extract 7.5 % SDS-PAGE. Dilution: 1:500
Immunohistochemistry-Paraffin: UGT1A6 Antibody [NBP1-33743] - Paraffin-embedded OV90 xenograft, using antibody at 1:100 dilution.
Western Blot: UGT1A6 Antibody [NBP1-33743] - Sample (30 ug of whole cell lysate) A: A431 B: H1299 7. 5% SDS PAGE; antibody diluted at 1:1000.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.56 mg/ml

Order Details

UGT1A6 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human UGT1A6. The exact sequence is proprietary.
Localization
Microsome, Endoplasmic reticulum membrane, Single-pass membrane protein
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
UGT1A6
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.56 mg/ml
Purity
Immunogen affinity purified

Alternate Names for UGT1A6 Antibody

  • GNT1UDPGT 1-6
  • HLUGP
  • HLUGP1
  • MGC29860
  • Phenol-metabolizing UDP-glucuronosyltransferase
  • UDP glucuronosyltransferase 1 family, polypeptide A6
  • UDP glycosyltransferase 1 family, polypeptide A6
  • UDP-glucuronosyltransferase 1 family polypeptide A6s
  • UDP-glucuronosyltransferase 1-6
  • UDP-glucuronosyltransferase 1A6
  • UDP-glucuronosyltransferase 1-F
  • UDPGT
  • UGT1
  • UGT1*6
  • UGT1.6
  • UGT1-06
  • UGT1A6S
  • UGT-1F
  • UGT1FEC 2.4.1.17

Background

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol UGT1A6