u-Plasminogen Activator/Urokinase Antibody (U-16) [Alexa Fluor® 532]

• Reactivity: Hu
• Applications: WB, ELISA, IHC
• Clone: U-16
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 532

u-Plasminogen Activator/Urokinase Antibody (U-16) [Alexa Fluor® 532] Summary

• Immunogen: Native human uPA
• Epitope: Binds to the B-chain of uPA
• Specificity: It is specific for human uPA. No reaction with human tissue plasminogen activator (tPA) when tested by ELISA, immunoblotting and enzyme inhibition and no reaction with any other human plasma proteins when tested by immunoblotting. Binds single and two-chain uPA and uPA/PAI-1 complexes. A reaction is seen with LMW-uPA but not with amino terminal fregment (ATF).
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PLAU
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Alternate Names for u-Plasminogen Activator/Urokinase Antibody (U-16) [Alexa Fluor® 532]

• ATF
• EC 3.4.21
• EC 3.4.21.73
• plasminogen activator, urokinase
• PLAU
• uPA
• u-PA
• uPlasminogen Activator
• u-Plasminogen Activator
• urinary
• Urokinase
• urokinase-type plasminogen activator

Background

Urokinase specifically cleave the zymogen plasminogen to form the active enzyme plasmin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PLAU