TTF-1 / NKX2-1 Antibody (SPM150) [DyLight 350]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC-Fr, IHC-P
Clone
SPM150
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 350

TTF-1 / NKX2-1 Antibody (SPM150) [DyLight 350] Summary

Immunogen
Rat full length TTF-1 recombinant protein
Localization
Nuclear
Marker
Thyroid & Lung Epithelial Marker
Specificity
Recognizes a protein of 40kDa, identified as Thyroid transcription factor-1 (TTF-1). TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates.Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
NKX2-1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin

Reactivity Notes

Shows broad species reactivity.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for TTF-1 / NKX2-1 Antibody (SPM150) [DyLight 350]

  • BCH
  • benign chorea
  • BHC
  • Homeobox protein NK-2 homolog A
  • homeobox protein Nkx-2.1
  • NK2 homeobox 1
  • NK-2 homolog A
  • NKX2.1
  • NKX2-1
  • NKX2A
  • NKX2ANKX2.1
  • T/EBP
  • Thyroid nuclear factor 1
  • Thyroid transcription factor 1BHC
  • TITF1
  • TITF1TEBP
  • TTF1
  • TTF-1
  • TTF1BCH
  • TTF-1NK-2

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for TTF-1 / NKX2-1 Antibody (NBP2-34742UV) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 405 NBP2-34742AF405
Alexa Fluor 488 NBP2-34742AF488
Alexa Fluor 647 NBP2-34742AF647
Alexa Fluor 700 NBP2-34742AF700
Alexa Fluor 750 NBP2-34742AF750
Allophycocyanin NBP2-34742APC
Biotin NBP2-34742B
DyLight 350 NBP2-34742UV
DyLight 405 NBP2-34742V
DyLight 488 NBP2-34742G
DyLight 550 NBP2-34742R
DyLight 650 NBP2-34742C
DyLight 680 NBP2-34742FR
DyLight 755 NBP2-34742IR
HRP NBP2-34742H
Janelia Fluor 549 NBP2-34742JF549
Janelia Fluor 646 NBP2-34742JF646
PE NBP2-34742PE
PerCP NBP2-34742PCP

Additional TTF-1 / NKX2-1 Products

Bioinformatics Tool for TTF-1 / NKX2-1 Antibody (NBP2-34742UV)

Discover related pathways, diseases and genes to TTF-1 / NKX2-1 Antibody (NBP2-34742UV). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for TTF-1 / NKX2-1 Antibody (NBP2-34742UV)

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Calculators

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Bioinformatics

Gene Symbol NKX2-1