TSPAN8/TM4SF3 Antibody

Western Blot: TSPAN8/TM4SF3 Antibody [NBP1-51942] - (0.01ug/ml) staining of Human Colon lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

TSPAN8/TM4SF3 Antibody Summary

• Description: Novus Biologicals Goat TSPAN8/TM4SF3 Antibody (NBP1-51942) is a polyclonal antibody validated for use in WB and ELISA. Anti-TSPAN8/TM4SF3 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence QRPCQSYNGKQVYKE corresponding to internal region according to NP_004607.1.
• Epitope: QRPCQSYNGKQVYKE
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: TSPAN8
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:16000
  • Western Blot 0.01 - 0.03 ug/ml
• Application Notes: WB: Approx. 24 kDa band observed in human colon lysates (calculated MW of 26.0 kDa band according to NP_004607.1).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for TSPAN8/TM4SF3 Antibody

• CO-029
• tetraspanin 8
• TM4SF3
• TM4SF3tspan-8
• Transmembrane 4 superfamily member 3tetraspanin-8
• TSPAN8
• Tspan-8
• Tumor-associated antigen CO-029

Background

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TSPAN8/TM4SF3 Antibody (NBP1-51942)(1)

Publication using NBP1-51942

• Grarup N, Andersen G, Krarup NT et al. Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes. Diabetes 2008-09-01 [PMID: 18567820]

Bioinformatics

• Gene Symbol: TSPAN8
• Entrez:
  • 7103(Human)
• Uniprot:
  • NP_004607.1(Human)