Tryptophan Hydroxylase 1/TPH-1 Antibody (508417) [Alexa Fluor® 532]

• Reactivity: Hu
• Applications: WB, IP
• Clone: 508417
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 532

Tryptophan Hydroxylase 1/TPH-1 Antibody (508417) [Alexa Fluor® 532] Summary

• Immunogen: S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Tryptophan Hydroxylase 1/TPH‑1
  Met102-Pro403
  Accession # P17752
• Specificity: Detects human Tryptophan Hydroxylase 1/TPH‑1 in direct ELISAs and Western blots.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Tryptophan Hydroxylase 1/TPH-1 Antibody (508417) [Alexa Fluor® 532]

• EC 1.14.16
• EC 1.14.16.4
• indoleacetic acid-5-hydroxylase
• L-tryptophan hydroxylase
• MGC119994
• TPH
• TPH-1
• TPRH
• TRPH
• tryptophan 5-hydroxylase 1
• Tryptophan 5-monooxygenase 1
• tryptophan hydroxylase (tryptophan 5-monooxygenase)
• Tryptophan Hydroxylase 1

Background

Tryptophan Hydroxylase-1 (TPH-1) is a member of the pterin-dependent aromatic acid hydroxylase family. It catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The amino acid sequence of human TPH-1 is 96%, 90%, and 87% identical to that of cow, mouse, and chicken.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.