TRRAP Antibody

Images

 
Western Blot: TRRAP Antibody [NB100-58811] - Detection of Human and Mouse TRRAP on HeLa whole cell lysate using NB100-58811. TRRAP was also immunoprecipitated by rabbit anti-TRRAP antibody NB100-58810.
Proximity Ligation Assay: TRRAP Antibody [NB100-58811] - Secondary-Conjugate Duolink II PLA in Hela Cells. Goat anti-human DMAP1 (NB100-256) and rabbit anti-human TRRAP (NB100-58811). Image merged from DAPI (2ms) and ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IP, PLA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml
 

Independent Antibodies

 

Biological Strategies

     

Order Details

TRRAP Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 3809 and 3859 of human transformation/transcription domain-associated protein using the numbering given in entry AAD04629.1 (GeneID 8295).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRRAP
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 2-5 mcg/mg
  • Proximity Ligation Assay 1:200-1:4000

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TRRAP Antibody

  • 350/400 kDa PCAF-associated factor
  • FLJ10671
  • PAF350/400
  • PAF400
  • PAF400STAF40
  • STAF40
  • Tra1 homolog
  • Tra1
  • transformation/transcription domain-associated protein
  • TR-AP
  • TRRAP

Background

The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins. It is an adapter protein, which is found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT), which gives a specific tag for epigenetic transcription activation. TRRAP plays a central role in MYC (c-Myc) transcription activation, and also participates in cell transformation by MYC. It is required for TP53/p53-, E2F1- and E2F4-mediated transcription activation. It most likely acts by linking transcription factors such as E1A, MYC or E2F1 to HAT complexes such as STAGA thereby allowing transcription activation and it is probably not required in the steps following histone acetylation in processes of transcription activation. TRRAP may also be required for the mitotic checkpoint and normal cell cycle progression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NB600-335
Species: Hu, Mu, Ec, NA
Applications: WB, ELISA, ICC/IF, IHC-Fr, IP
NBP2-17017
Species: Hu, Mu
Applications: WB, ICC/IF
NBP2-24613
Species: Hu
Applications: WB, Simple Western, IHC-P
NB100-104
Species: Hu, Mu
Applications: WB, ELISA, Flow, IB, ICC/IF, IHC, IHC-P, IP
NBP2-07996
Species: Hu
NBP2-52486
Species: Hu
Applications: WB, ELISA, Flow, IHC, IHC-P, CyTOF-ready, ICC, IF
NBP1-47602
Species: Bv
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP
NB300-619
Species: Hu, Mu, Rt, Bv, Ch, Ha
Applications: WB, ICC/IF, IHC, IHC-P, IP
NBP1-87404
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
NB100-381
Species: Hu
Applications: WB, ChIP, IP, PLA
NB100-57524
Species: Hu
Applications: WB, IHC, IHC-P, IP
H00008850-M04
Species: Hu
Applications: WB, ELISA, ICC/IF
NBL1-11569
Species: Hu
NBP1-76729
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
H00008360-R01
Species: Hu
NBL1-11570
Species: Hu
NBP2-10888
Species: Hu
H00008365-M01
Species: Hu
Applications: ELISA, ICC/IF
NBL1-11567
Species: Hu

Publications for TRRAP Antibody (NB100-58811) (0)

There are no publications for TRRAP Antibody (NB100-58811).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for TRRAP Antibody (NB100-58811) (0)

There are no reviews for TRRAP Antibody (NB100-58811). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for TRRAP Antibody (NB100-58811) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional TRRAP Products

Bioinformatics Tool for TRRAP Antibody (NB100-58811)

Discover related pathways, diseases and genes to TRRAP Antibody (NB100-58811). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for TRRAP Antibody (NB100-58811)

Discover more about diseases related to TRRAP Antibody (NB100-58811).
 

Pathways for TRRAP Antibody (NB100-58811)

View related products by pathway.

PTMs for TRRAP Antibody (NB100-58811)

Learn more about PTMs related to TRRAP Antibody (NB100-58811).
 

Research Areas for TRRAP Antibody (NB100-58811)

Find related products by research area.

Blogs on TRRAP

There are no specific blogs for TRRAP, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our TRRAP Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol TRRAP
Entrez
Uniprot