TRRAP Products

Antibodies
TRRAP Antibody
TRRAP Antibody
AF7365
Species: Hu, Mu, Rt
Applications: WB
Host: Sheep Polyclonal
TRRAP Antibody
TRRAP Antibody
NBP1-87350
Species: Hu, Mouse, Rat
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
TRRAP Antibody
TRRAP Antibody
NB100-58811
Species: Hu, Mu
Applications: WB, IP, PLA
Host: Rabbit Polyclonal
Proteins
TRRAP Partial Recombinant Pro ...
TRRAP Partial Recombinant Protein
H00008295-Q01
Species: Hu
Applications: WB, ELISA, PA
TRRAP Recombinant Protein Ant ...
TRRAP Recombinant Protein Antigen
NBP1-87350PEP
Species: Hu
Applications: AC
RNAi
TRRAP RNAi
TRRAP RNAi
H00008295-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins. It is an adapter protein, which is found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT), which gives a specific tag for epigenetic transcription activation. TRRAP plays a central role in MYC (c-Myc) transcription activation, and also participates in cell transformation by MYC. It is required for TP53/p53-, E2F1- and E2F4-mediated transcription activation. It most likely acts by linking transcription factors such as E1A, MYC or E2F1 to HAT complexes such as STAGA thereby allowing transcription activation and it is probably not required in the steps following histone acetylation in processes of transcription activation. TRRAP may also be required for the mitotic checkpoint and normal cell cycle progression.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Product By Gene ID 8295
Alternate Names
  • 350/400 kDa PCAF-associated factor
  • Tra1 homolog
  • Tra1
  • FLJ10671
  • TR-AP
  • PAF400STAF40
  • PAF350/400
  • transformation/transcription domain-associated protein

Research Areas for TRRAP

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Protein Kinase

Bioinformatics Tool for TRRAP

Discover related pathways, diseases and genes to TRRAP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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