TRP7 Antibody

• Reactivity: Ch, Hu, Mu, Rt, Ca
• Applications: WB, ELISA, IP
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

TRP7 Antibody Summary

• Immunogen: Peptide with sequence KLCKSKAKSCEND corresponding to internal region according to NP_001161049.1, NP_001161048.1.
• Epitope: internal region
• Specificity: This antibody is expected to cross-react with isoform 1, 2 and 3 (NP_065122.1; NP_001161049.1; NP_001161048.1).
• Predicted Species: Human (100%), Mouse (100%), Rat (100%), Canine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: TRPC7
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Peptide ELISA Detection limit 1:32000
  • Western Blot

Reactivity Notes

Expected from sequence similarity: Human, Mouse, Rat, Canine

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for TRP7 Antibody

• hTRP7
• KNP3
• likley ortholog of mouse transient receptor potential cation channel, subfamilyC, member 7
• putative capacitative calcium channel
• short transient receptor potential channel 7
• transient receptor potential cation channel, subfamily C, member 7
• transient receptor potential-related channel 7, a novel putative Ca2+ channelprotein10TRPM2
• Transient receptor protein 7
• TRP7
• TRP-7
• TrpC7

Background

TRP7 is thought to form a receptor-activated non-selective calcium permanent cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG). May also be activated by intracellular calcium store depletion.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TRP7 Antibody (NBP1-44058)(2)

Publications using NBP1-44058

• Sabourin J, Robin E, Raddatz E. A key role of TRPC channels in the regulation of electromechanical activity of the developing heart. Cardiovasc Res 2011-11-01 [PMID: 21672930]
• Eder P, Groschner K. TRPC3/6/7: Topical aspects of biophysics and pathophysiology. Channels (Austin) 2008-03-29 [PMID: 18849655]

Bioinformatics

• Gene Symbol: TRPC7
• Entrez:
  • 57113(Human)
  • 26946(Mouse)
  • 282822(Rat)
• Uniprot:
  • NP_065122.1(Human)