TrkC Antibody (7H6) Summary
Purified recombinant extracellular fragment of human NTRK3 (aa32-429) fused with hIgGFc tag expressed in HEK293 cells.
Test in a species/application not listed above to receive a full credit towards a future purchase.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.03% Sodium Azide
This product is unpurified. The exact concentration of antibody is not quantifiable.
This antibody is useful in Western Blot, Immunohistochemistry-Paraffin, ELISA. Although not tested this antibody may be useful in Immunohistochemistry-Frozen.
Alternate Names for TrkC Antibody (7H6)
- EC 2.7.10
- EC 18.104.22.168
- ETS related protein-neurotrophic receptor tyrosine kinase fusion protein
- ETV6-NTRK3 fusion
- Neurotrophic tyrosine kinase receptor type 3
- neurotrophic tyrosine kinase, receptor, type 3
- NT 3 receptor
- NT-3 growth factor receptor
- TrkC tyrosine kinase
- TRKCneurotrophin 3 receptor
- tyrosine kinase receptor C
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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Blogs on TrkC.
TrkB: Bridging Ontogenesis and Oncogenesis
Tropomyosin receptor kinase B (TrkB) is a member of the Trk receptor tyrosine kinases family consisting of TrkA, TrkB and TrkC. The sequence of these family members is highly conserved. Interaction of brain-derived neurotrophic factor (BDNF) with its... Read full blog post.
TrkB: Docking for Neurotrophins and Beyond.
Tropomyosin receptor kinase B (TrkB) is a member of the Trk receptor tyrosine kinases family consisting of TrkA, TrkB and TrkC. The sequence of these family members is highly conserved. TrK's are activated by several neurotrophins, which are small pro... Read full blog post.