TRIM37 Antibody (2D11)

Sandwich ELISA: TRIM37 Antibody (2D11) [H00004591-M01] - Detection limit for recombinant GST tagged TRIM37 is approximately 0.3ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA, S-ELISA
• Clone: 2D11
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

TRIM37 Antibody (2D11) Summary

• Immunogen: TRIM37 (NP_056109, 865 a.a. ~ 964 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. GHLEGLQMTDLENNSETGELQPVLPEGASAAPEEGMSSDSDIECDTENEEQEEHTSVGGFHDSFMVMTQPPDEDTHSSFPDGEQIGPEDLSFNTDENSGR
• Specificity: TRIM37 - tripartite motif-containing 37
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: TRIM37
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for TRIM37 Antibody (2D11)

• EC 6.3.2.-
• KIAA0898Tripartite motif-containing protein 37
• Mulibrey nanism protein
• MULRING-B-box-coiled-coil protein
• POB1E3 ubiquitin-protein ligase TRIM37
• TEF3
• tripartite motif containing 37
• tripartite motif-containing 37

Background

This protein is a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TRIM37
• Entrez:
  • 4591(Human)
• OMIM:
  • 253(Human)
• Uniprot:
  • NP_056109(Human)