Human and Mouse. Predicted cross-reactivity based on sequence identity: Rhesus Monkey (100%).
Alternate Names for TRIM23 Antibody
ADP-ribosylation factor domain protein 1, 64kDa
ADP-ribosylation factor domain-containing protein 1
ARD1GTP-binding protein ARD-1
ARF domain protein 1
E3 ubiquitin-protein ligase TRIM23
RNF46RING finger protein 46
tripartite motif containing 23
tripartite motif protein TRIM23
tripartite motif-containing 23
Tripartite motif-containing protein 23
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.