TREX1 Antibody (41M5F2) [DyLight 550]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-P
Clone
41M5F2
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 550

TREX1 Antibody (41M5F2) [DyLight 550] Summary

Immunogen
Within the range of amino acids 211-350 of human TREX1 were used as immunogen for the antibody.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TREX1
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
There are numerous isoforms of TREX1. Researchers are encouraged to use an online tool like NCBI's BLAST to determine if the antibody is suitable for use in their testing. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for TREX1 Antibody (41M5F2) [DyLight 550]

  • 3'-5' exonuclease TREX1
  • AGS1
  • Aicardi-Goutieres syndrome 1
  • CRV
  • DKFZp434J0310
  • DNase III
  • DRN3
  • EC 3.1.11.2
  • HERNS
  • three prime repair exonuclease 1,3' repair exonuclease 1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Biotin Labeled NBP2-22394B
DyLight 350 Labeled NBP2-22394UV
DyLight 405 Labeled NBP2-22394V
DyLight 488 Labeled NBP2-22394G
DyLight 650 Labeled NBP2-22394C
DyLight 680 Labeled NBP2-22394FR
DyLight 755 Labeled NBP2-22394IR
HRP Labeled NBP2-22394H

Additional TREX1 Products

Bioinformatics Tool for TREX1 Antibody (NBP2-22394R)

Discover related pathways, diseases and genes to TREX1 Antibody (NBP2-22394R). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for TREX1 Antibody (NBP2-22394R)

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Pathways for TREX1 Antibody (NBP2-22394R)

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PTMs for TREX1 Antibody (NBP2-22394R)

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Research Areas for TREX1 Antibody (NBP2-22394R)

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Blogs on TREX1.

Dinosaur Protein Names: Infographic
Trex1 the protein is involved in DNA damage response. Tyrannosaurus rex (T. rex) the dinosaur lived during the Cretaceous Period. Raptor the protein is a regulator of mTOR activity. Velociraptors the dinosaurs lived during the Cretaceous Period. Learn...  Read full blog post.

Trex1 (3'-5' exonuclease TREX1, DNase III)
This gene encodes the major 3' to 5' DNA exonuclease in human cells. The protein is a non-processive exonuclease that appears to provide proofreading for checkpoint signaling after DNA damage in response to oxidative stress and apoptosis. It is ubiqui...  Read full blog post.

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Bioinformatics

Gene Symbol TREX1