TREX1 Antibody (2F10) - Azide and BSA Free

Western Blot: TREX1 Antibody (2F10) [H00011277-M01] - Analysis of TREX1 expression in transfected 293T cell line by TREX1 monoclonal antibody (M01), clone 2F10.Lane 1: TREX1 transfected lysate (Predicted MW: 38.9 KDa).Lane 2: Non-transfected lysate.

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 2F10
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

TREX1 Antibody (2F10) - Azide and BSA Free Summary

• Immunogen: TREX1 (NP_057465, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MGPGARRQGRIVQGRPEMCFCPPPTPLPPLRILTLGTHTPTPCSSPGSAAGTYPTMGSQALPPGPMQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALE
• Specificity: TREX1 - three prime repair exonuclease 1
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: TREX1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody Reactive against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for TREX1 Antibody (2F10) - Azide and BSA Free

• 3'-5' exonuclease TREX1
• AGS1
• Aicardi-Goutieres syndrome 1
• CRV
• DKFZp434J0310
• DNase III
• DRN3
• EC 3.1.11.2
• HERNS
• three prime repair exonuclease 1,3' repair exonuclease 1

Background

This gene encodes the major 3'->5' DNA exonuclease in human cells. The protein is a non-processive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TREX1
• Entrez:
  • 11277(Human)
• OMIM:
  • 606605(Human)
• Uniprot:
  • NP_057465(Human)