Transglutaminase 7/TGM7 Antibody (602708) [Alexa Fluor™ Plus 647]

• Reactivity: Hu
• Clone: 602708
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor Plus 647

Transglutaminase 7/TGM7 Antibody (602708) [Alexa Fluor™ Plus 647] Summary

• Specificity: Detects human Transglutaminase 7/TGM7 in direct ELISAs and Western blots. In direct ELISAs, no cross‑reactivity with recombinant human TGM2, 3, 4, or recombinant mouse TGM2 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Transglutaminase 7/TGM7 Antibody (602708) [Alexa Fluor™ Plus 647]

• protein-glutamine gamma-glutamyltransferase Z
• TG(Z)
• TGase Z
• TGase-7
• TGM7
• TGMZ
• TGMZEC 2.3.2.13
• TGZ
• Transglutaminase 7
• Transglutaminase Z
• transglutaminase-7

Background

Transglutaminase 7 (TGM7), also known as protein-glutamine gamma -glutamyltransferase Z, TGase Z and TGZ, is an 80 kDa, widely expressed member of the Transglutaminase superfamily and family. Human Transglutaminase 7 is 710 amino acids (aa) in length and contains a Transglutaminase family, C-terminal Ig like domain (aa 608‑705). Human Transglutaminase 7 shares 78% aa identity with mouse Transglutaminase 7. Like other Transglutaminases, Transglutaminase 7 is an enzyme that stabilizes protein assembly through the formation of intra- or intermolecular N epsilon ( gamma -glutamyl)lysine bonds. It catalyzes a calcium-dependent transferase reaction between the gamma -carboxamide group of a peptide-bound glutamine residue and various primary amines, most commonly the epsilon -amino group of lysine residues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.