TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody - N-terminal

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody - N-terminal Summary

• Immunogen: A synthetic peptide corresponding to a region near the amino terminus of human TR alpha/NR1A1/Thyroid Hormone Receptor alpha isoform 1 protein.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: THRA
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: This antibody has been tested for use in ELISA and western blotting.
  
  Suggested applications: ChIP; IHC; Multiplex

Reactivity Notes

BLAST analysis was used to suggest cross-reactivity with THRA from mouse, human and rat based on a 100% homology with the immunizing sequence. Cross-reactivity with THRA from other sources has not been determined.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
• Preservative: 0.01% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody - N-terminal

• AR7
• c-ERBA-1
• c-erbA-alpha
• EAR7
• EAR-7
• EAR-7.1/EAR-7.2
• ERBA
• ERBA1thyroid hormone receptor, alpha (avian erythroblastic leukemia viral (v-erb-a)oncogene homolog)
• ERBA-related 7
• MGC000261
• MGC43240
• NR1A 1
• NR1A1
• NR1A1THRA3
• Nuclear receptor subfamily 1 group A member 1
• THRA
• THRA1ERB-T-1
• THRA2
• thyroid hormone receptor alpha
• thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a)oncogene homolog, avian)
• TR alpha
• triiodothyronine receptor
• v-ErbA1
• V-erbA-related protein 7

Background

Thyroid Hormone Receptor alpha is encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: THRA