TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (H2804) [Unconjugated]

• Reactivity: Hu
• Applications: WB, IHC, ELISA
• Clone: H2804
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Suitable Sample Type: 23015

TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (H2804) [Unconjugated] Summary

• Immunogen: Recombinant human TR alpha/NR1A1
  aa 2-51
• Specificity: This antibody specifically recognizes human TR alpha and cross-reacts with mouse and rat TR alpha. The antibody does not cross-react with human TR beta. Not yet tested in other species.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: THRA
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
  • Immunohistochemistry 5-15 ug/mL
  • Direct ELISA

Packaging, Storage & Formulations

• Storage: This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
• Buffer: A liquid formulation in physiologic saline with 0.1% NaN₃.
• Preservative: 0.1% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (H2804) [Unconjugated]

• AR7
• c-ERBA-1
• c-erbA-alpha
• EAR7
• EAR-7
• EAR-7.1/EAR-7.2
• ERBA
• ERBA1thyroid hormone receptor, alpha (avian erythroblastic leukemia viral (v-erb-a)oncogene homolog)
• ERBA-related 7
• MGC000261
• MGC43240
• NR1A 1
• NR1A1
• NR1A1THRA3
• Nuclear receptor subfamily 1 group A member 1
• THRA
• THRA1ERB-T-1
• THRA2
• thyroid hormone receptor alpha
• thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a)oncogene homolog, avian)
• TR alpha
• triiodothyronine receptor
• v-ErbA1
• V-erbA-related protein 7

Background

Thyroid Hormone Receptor alpha (TR alpha, THRA; NR1A1) is a member of the Nuclear Hormone Receptor superfamily. The ligands for TR alpha are the thyroid hormones, which exist in two forms: T4 and T3. TR alpha plays a critical role in the differentiation, growth, metabolism and physiology of a wide variety of tissues. The major partners of TRs are the Retinoid X Receptors (RXRs), which strongly enhance their ability to bind to specific DNA sequences and contribute to the specificity of TR.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: THRA