TOM70 Antibody Blocking Peptide

Product Discontinued

TOM70 Antibody Blocking Peptide Summary

• Description: A blocking peptide containing 15 amino acids near the center of human TOM70.

  Source: Synthetic

  (Accession #: NP_055635)

• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: TOMM70
• Purity: N/A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NBP1-77342.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
• Preservative: 0.02% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: N/A

Alternate Names for TOM70 Antibody Blocking Peptide

• FLJ90470
• KIAA0719
• mitochondrial import receptor subunit TOM70
• Mitochondrial precursor proteins import receptor
• TOM70
• Translocase of outer membrane 70 kDa subunit
• translocase of outer mitochondrial membrane 70 (yeast) homolog A
• translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
• translocase of outer mitochondrial membrane 70 homolog A (yeast)

Background

Functional mitochondria require up to 1000 proteins to function properly, with 99% synthesized as precursors in the cytoplasm and transported into the mitochondria with the aid of cytosolic chaperones and mitochondrial translocators (import components). Proteins to be imported are chaperoned to the mitochondria by the cytosolic heat shock protein (cHSP70) and are immediately pursued by Translocators of the Outer Membrane (TOMs), followed by transient interactions of the unfolded proteins with Translocators of the Inner Membrane (TIMs). TOMM70A is ubiquitously expressed in human tissues and localizes in the mitochondria. TOMM70A could play a significant role in the import of nuclear-encoded mitochondrial proteins with internal targeting sites such as ADP/ATP carriers and the uncoupling proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: TOMM70