TOM70 293T Cell Transient Overexpression Lysate

Product Discontinued

TOM70 293T Cell Transient Overexpression Lysate Summary

• Description: Quality control test: Transient overexpression cell lysate was tested with Anti-TOMM70A antibody by Western Blots. Plasmid: pCMV-TOMM70A full-length
• Specificity: TOM70 293T Cell Transient Overexpression Lysate(Denatured)
• Gene: TOMM70

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)

Lysate Details for Array

• Type: 293T Cell Transient Overexpression
• Protein State: Denatured

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for TOM70 293T Cell Transient Overexpression Lysate

• FLJ90470
• KIAA0719
• mitochondrial import receptor subunit TOM70
• Mitochondrial precursor proteins import receptor
• TOM70
• Translocase of outer membrane 70 kDa subunit
• translocase of outer mitochondrial membrane 70 (yeast) homolog A
• translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
• translocase of outer mitochondrial membrane 70 homolog A (yeast)

Background

Functional mitochondria require up to 1000 proteins to function properly, with 99% synthesized as precursors in the cytoplasm and transported into the mitochondria with the aid of cytosolic chaperones and mitochondrial translocators (import components). Proteins to be imported are chaperoned to the mitochondria by the cytosolic heat shock protein (cHSP70) and are immediately pursued by Translocators of the Outer Membrane (TOMs), followed by transient interactions of the unfolded proteins with Translocators of the Inner Membrane (TIMs). TOMM70A is ubiquitously expressed in human tissues and localizes in the mitochondria. TOMM70A could play a significant role in the import of nuclear-encoded mitochondrial proteins with internal targeting sites such as ADP/ATP carriers and the uncoupling proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: TOMM70