TNIP2 Antibody - BSA Free

Immunohistochemistry: TNIP2 Antibody - BSA Free [NBP3-45174] - Immunohistochemistry of paraffin-embedded human liver using (TNIP2 antibody) at dilution of 1:100

Western Blot: TNIP2 Antibody - BSA Free [NBP3-45174] - HepG2 cells were subjected to SDS PAGE followed by western blot with (TNIP2 antibody) at dilution of 1:500

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

TNIP2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit TNIP2 Antibody - BSA Free (NBP3-45174) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: TNFAIP3 interacting protein 2. (Uniprot# Q8NFZ5)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TNIP2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence 1:20-1:200
  • Immunohistochemistry 1:20-1:200
  • Western Blot 1:500-1:2000
• Theoretical MW: 50 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for TNIP2 Antibody - BSA Free

• A20-binding inhibitor of NF-kappa-B activation 2
• A20-binding inhibitor of NF-kappaB activation-2
• ABIN-2
• ABIN2KLIP
• Fetal liver LKB1-interacting protein
• FLIP1DKFZp434J1313
• MGC4289
• TNFAIP3 interacting protein 2
• TNFAIP3-interacting protein 2

Background

ABIN-2, TNFAIP3 interacting protein 2, binds to the COOH-terminal zinc finger domain of A20. NF-kB activation induced by TNF and interleukin-1 is inhibited by overexpression of ABIN-2. The latter also inhibits NF-kB activation induced by overexpression of receptor-interacting protein or TNF receptor-associated factor 2. A-20 binding Inhibitor of Nuclear Factor-kappaB (NF-kB)Activation (ABIN-2) binds to A-20. ABIN-2 interferes with NF-kB activation upstream of the IKK complex and might contribute to NF-kB inhibitory function of A-20.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TNIP2