TMEFF2/Tomoregulin-2 Antibody

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

TMEFF2/Tomoregulin-2 Antibody Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human TMEFF2/Tomoregulin‑2
  Arg34-Val320
  Accession # Q9UIK5
• Specificity: Detects human TMEFF2/Tomoregulin‑2 in direct ELISAs and Western blots. In direct ELISAs, approximately 15% cross-reactivity with recombinant human TMEFF1 is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: TMEFF2
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TMEFF2/Tomoregulin-2 Antibody

• CT120.2
• HPP1member 2
• Hyperplastic polyposis protein 1
• TENB2
• TMEFF2
• Tomoregulin2
• Tomoregulin-2
• TPEFtomoregulin
• TR-2
• transmembrane protein TENB2
• transmembrane protein with EGF-like and two follistatin-like domains 2
• Transmembrane protein with EGF-like and two follistatin-like domains
• TRtomoregulin-2

Background

TMEFF2 is expressed primarily in normal brain and prostate. Soluble TMEFF2 extracellular domain is generated by proteolytic cleavage of the transmembrane protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TMEFF2/Tomoregulin-2 Antibody (AF1867)(1)

Publication using AF1867

• Ali N, Knauper V Phorbol ester-induced shedding of the prostate cancer marker transmembrane protein with epidermal growth factor and two follistatin motifs 2 is mediated by the disintegrin and metalloproteinase-17. J. Biol. Chem., 2007-10-17;282(52):37378-88. 2007-10-17 [PMID: 17942404] (Western Blot, Human)

Bioinformatics

• Gene Symbol: TMEFF2
• Uniprot:
  • Q9UIK5()