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Thymidylate Synthase Antibody

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Summary
Product Discontinued
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    • Catalog Number
      NBP1-36638
    • Availability
      Product Discontinued

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Thymidylate Synthase Antibody Summary

Immunogen
A synthetic peptide derived from C-terminus of human TS protein
Specificity
This product is specific for TS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TYMS
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:100
Application Notes
This product is useful for Immunohistochemistry Paraffin. This product has a prediluted size available with catalog number NBP1-36642.
Reviewed Applications
Read 1 Review rated 4
using
NBP1-36638 in the following applications:

Reactivity Notes

This product is specific for Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.6) and 1.0% BSA
Preservative
0.1% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Thymidylate Synthase Antibody

  • EC 2.1.1.45
  • HsT422
  • MGC88736
  • OK/SW-cl.29
  • Thymidylate Synthase
  • thymidylate synthetase
  • TMSTsase
  • TS
  • TSase
  • TSHST422
  • TYMS

Background

Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Thymidylate Synthase Antibody (NBP1-36638) (0)

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Review for Thymidylate Synthase Antibody (NBP1-36638) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using NBP1-36638:
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 IHC-P
(1)
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Images Ratings Applications Species Date Details
Immunohistochemistry-Paraffin Thymidylate Synthase NBP1-36638
Enlarge 		4
reviewed by:
Ranjuna Weeraskera
  IHC-P Human 10/28/2011
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Summary

ApplicationImmunohistochemistry-Paraffin
Sample TestedPancreatic tumor
SpeciesHuman

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Immunohistochemistry-Paraffin Thymidylate Synthase NBP1-36638
Enlarge
 Ranjuna Weeraskera
10/28/2011
Application:  IHC-P
Species: Human
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Bioinformatics

Gene Symbol TYMS
Entrez
Uniprot