Thromboxane A2 R/TBXA2R Antibody (SR1893) - BSA Free

Western Blot: Thromboxane A2 R/TBXA2R Antibody (SR1893) [NBP3-22509] - Western blot analysis using NBP3-22509 in human platelet cell lysate.

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: SR1893
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Thromboxane A2 R/TBXA2R Antibody (SR1893) - BSA Free Summary

• Description: Novus Biologicals Rabbit Thromboxane A2 R/TBXA2R Antibody (SR1893) - BSA Free (NBP3-22509) is a recombinant monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human Thromboxane A2 R/TBXA2R (Uniprot #: P21731)
• Specificity: Detects endogenous levels of total Thromboxane A2 R/TBXA2R
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: TBXA2R
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:2000
• Theoretical MW: 50 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Thromboxane A2 R/TBXA2R Antibody (SR1893) - BSA Free

• BDPLT13
• Prostanoid TP Receptor
• TBXA2R
• Thromboxane A2 R
• thromboxane A2 receptor
• Thromboxane A2R
• TP
• TXA2-R
• TXA2R2

Background

The thromboxane A2 receptor (TBXA2R) is a member of the Prostanoid Receptor subfamily. TBXA2R performs an essential role in hemostasis by interacting with thromboxane A2 to induce platelet aggregation. Thromboxane A2 has been implicated in myocardial infarct, stroke, and asthma. Additionally, thromboxane-prostanoid receptors have been implicated in the pathogenesis of cardiovascular diseases. Changes in TBXA2R function have also been linked to a hereditary bleeding disorder. The thromboxane A2 receptor is encoded by a single gene that is alternatively spliced at the carboxyl terminus, resulting in two variants, TP (343 residues) and TP (407 residues) that share the first 328 amino acids.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TBXA2R